Near-Infrared Spectroscopy Used to Assess Physiological Muscle Adaptations in Exercise Clinical Trials: A Systematic Review
Using muscle oxygenation to evaluate the therapeutic effects of physical exercise in pathologies through near-infrared spectroscopy (NIRS) is of great interest. The aim of this review was to highlight the use of muscle oxygenation in exercise interventions in clinical trials and to present the techn...
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| Format: | Article |
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MDPI AG
2022-07-01
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| author | Marcelo Tuesta Rodrigo Yáñez-Sepúlveda Humberto Verdugo-Marchese Cristián Mateluna Ildefonso Alvear-Ordenes |
| author_facet | Marcelo Tuesta Rodrigo Yáñez-Sepúlveda Humberto Verdugo-Marchese Cristián Mateluna Ildefonso Alvear-Ordenes |
| author_sort | Marcelo Tuesta |
| collection | DOAJ |
| description | Using muscle oxygenation to evaluate the therapeutic effects of physical exercise in pathologies through near-infrared spectroscopy (NIRS) is of great interest. The aim of this review was to highlight the use of muscle oxygenation in exercise interventions in clinical trials and to present the technological characteristics related to the equipment used in these studies. PubMed, WOS, and Scopus databases were reviewed up to December 2021. Scientific articles that evaluated muscle oxygenation after exercise interventions in the sick adult population were selected. The PEDro scale was used to analyze the risk of bias (internal validity). The results were presented grouped in tables considering the risk of bias scores, characteristics of the devices, and the effects of exercise on muscle oxygenation. All the stages were carried out using preferred reporting items for systematic reviews and meta-analyses (PRISMA). The search strategy yielded 820 clinical studies, of which 18 met the eligibility criteria. This review detailed the characteristics of 11 NIRS devices used in clinical trials that used physical exercise as an intervention. The use of this technology made it possible to observe changes in muscle oxygenation/deoxygenation parameters such as tissue saturation, oxyhemoglobin, total hemoglobin, and deoxyhemoglobin in clinical trials of patients with chronic disease. It was concluded that NIRS is a non-invasive method that can be used in clinical studies to detect the effects of physical exercise training on muscle oxygenation, hemodynamics, and metabolism. It will be necessary to unify criteria such as the measurement site, frequency, wavelength, and variables for analysis. This will make it possible to compare different models of exercise/training in terms of time, intensity, frequency, and type to obtain more precise conclusions about their benefits for patients. |
| first_indexed | 2024-03-09T03:41:12Z |
| format | Article |
| id | doaj.art-1cc18fbb3d624ac692a46e5e363bae70 |
| institution | Directory Open Access Journal |
| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-09T03:41:12Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj.art-1cc18fbb3d624ac692a46e5e363bae702023-12-03T14:40:52ZengMDPI AGBiology2079-77372022-07-01117107310.3390/biology11071073Near-Infrared Spectroscopy Used to Assess Physiological Muscle Adaptations in Exercise Clinical Trials: A Systematic ReviewMarcelo Tuesta0Rodrigo Yáñez-Sepúlveda1Humberto Verdugo-Marchese2Cristián Mateluna3Ildefonso Alvear-Ordenes4Exercise and Rehabilitation Sciences Laboratory, School of Physical Therapy, Faculty of Rehabilitation Sciences, Universidad Andres Bello, Santiago 7591538, ChileApplied Physiology Laboratory (FISAP), Institute of Biomedicine (IBIOMED), University of León, 24071 León, SpainLaboratory of Sport Sciences, Centro de Medicina Deportiva Sports MD, Viña del Mar 2521156, ChilePhysical Education School, Pontificia Universidad Católica de Valparaíso, Valparaíso 2530388, ChileApplied Physiology Laboratory (FISAP), Institute of Biomedicine (IBIOMED), University of León, 24071 León, SpainUsing muscle oxygenation to evaluate the therapeutic effects of physical exercise in pathologies through near-infrared spectroscopy (NIRS) is of great interest. The aim of this review was to highlight the use of muscle oxygenation in exercise interventions in clinical trials and to present the technological characteristics related to the equipment used in these studies. PubMed, WOS, and Scopus databases were reviewed up to December 2021. Scientific articles that evaluated muscle oxygenation after exercise interventions in the sick adult population were selected. The PEDro scale was used to analyze the risk of bias (internal validity). The results were presented grouped in tables considering the risk of bias scores, characteristics of the devices, and the effects of exercise on muscle oxygenation. All the stages were carried out using preferred reporting items for systematic reviews and meta-analyses (PRISMA). The search strategy yielded 820 clinical studies, of which 18 met the eligibility criteria. This review detailed the characteristics of 11 NIRS devices used in clinical trials that used physical exercise as an intervention. The use of this technology made it possible to observe changes in muscle oxygenation/deoxygenation parameters such as tissue saturation, oxyhemoglobin, total hemoglobin, and deoxyhemoglobin in clinical trials of patients with chronic disease. It was concluded that NIRS is a non-invasive method that can be used in clinical studies to detect the effects of physical exercise training on muscle oxygenation, hemodynamics, and metabolism. It will be necessary to unify criteria such as the measurement site, frequency, wavelength, and variables for analysis. This will make it possible to compare different models of exercise/training in terms of time, intensity, frequency, and type to obtain more precise conclusions about their benefits for patients.https://www.mdpi.com/2079-7737/11/7/1073NIRSphysical exercisehemoglobinmuscle oximetry |
| spellingShingle | Marcelo Tuesta Rodrigo Yáñez-Sepúlveda Humberto Verdugo-Marchese Cristián Mateluna Ildefonso Alvear-Ordenes Near-Infrared Spectroscopy Used to Assess Physiological Muscle Adaptations in Exercise Clinical Trials: A Systematic Review Biology NIRS physical exercise hemoglobin muscle oximetry |
| title | Near-Infrared Spectroscopy Used to Assess Physiological Muscle Adaptations in Exercise Clinical Trials: A Systematic Review |
| title_full | Near-Infrared Spectroscopy Used to Assess Physiological Muscle Adaptations in Exercise Clinical Trials: A Systematic Review |
| title_fullStr | Near-Infrared Spectroscopy Used to Assess Physiological Muscle Adaptations in Exercise Clinical Trials: A Systematic Review |
| title_full_unstemmed | Near-Infrared Spectroscopy Used to Assess Physiological Muscle Adaptations in Exercise Clinical Trials: A Systematic Review |
| title_short | Near-Infrared Spectroscopy Used to Assess Physiological Muscle Adaptations in Exercise Clinical Trials: A Systematic Review |
| title_sort | near infrared spectroscopy used to assess physiological muscle adaptations in exercise clinical trials a systematic review |
| topic | NIRS physical exercise hemoglobin muscle oximetry |
| url | https://www.mdpi.com/2079-7737/11/7/1073 |
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