The correlation of number of parity and bone mineral density (BMD) in women: A systematic review and meta-analysis
Introduction: Osteoporosis is a major health problem in women throughout the world. Based on the available evidence, delivery can play an important role in women's bone mineral density. Therefore, this study was performed with aim to determine the correlation between parity and bone mineral den...
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| Format: | Article |
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Mashhad University of Medical Sciences
2019-04-01
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| Series: | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
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| Online Access: | https://ijogi.mums.ac.ir/article_13205_d4bae9a50987c290bdf6002338c04e81.pdf |
| _version_ | 1811328881375838208 |
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| author | Marzieh Saei Ghare Naz Farzaneh Rashidi Fakari Vida Ghasemi Zahra Kiani Giti Ozgoli |
| author_facet | Marzieh Saei Ghare Naz Farzaneh Rashidi Fakari Vida Ghasemi Zahra Kiani Giti Ozgoli |
| author_sort | Marzieh Saei Ghare Naz |
| collection | DOAJ |
| description | Introduction: Osteoporosis is a major health problem in women throughout the world. Based on the available evidence, delivery can play an important role in women's bone mineral density. Therefore, this study was performed with aim to determine the correlation between parity and bone mineral density through systematic review and.
Methods: In this systematic review and meta-analysis study, for finding the related articles, the databases of PubMed, Scopus, Cochran library and Web of Science databases were searched without time limitation and with English language restriction by using of the keywords of Parity and Bone Mineral Density (BMD) or Bone Mineral Content or bone density. The adapted Newcastle-Ottawa Scale was used to assess the quality of the cross-sectional articles. Funnel plot and Egger's test was used for publication bias assessing. Q-test and I2 index were used for evaluation of heterogeneity. Fisher’s 𝑟-to-𝑧 transformation was calculated for the studies.
Results: In this study, a total of 1336 papers were reviewed and 11 studies involving 5141 women were included in this meta-analysis. The decreasing trend in lumbar spine, femur and total hip BMD was observed in women with parity ≥5 compared to non-parity women. In nulliparous women, the mean of BMD in lumbar spine was (M:0.93 ,95%CI;0.75-1.11, Phetrogeneity <0.001), in femur (M:0.84 95%CI;0.60-1.09, Phetrogeneity <0.001) and in hip (M:0.86, 95%CI;0.84-0.89, Phetrogeneity =0.001). The mean of BMD in postmenopausal women was lower in lumbar, femur and hip. In African women, the mean of BMD in three sites were higher. There was no reverse moderate correlation between parity and lumbar BMD -0.22 (95% CI -0.14, -0.30) and hip BMD -0.21 (95% CI -0.12, -0.29).
Conclusion: The mean BMD was higher in nulliparous women. There was inverse correlation between lumbar BMD and hip BMD with parity, but because of high heterogeneity in analyzed subgroups, performing cohort studies is recommended. |
| first_indexed | 2024-04-13T15:33:58Z |
| format | Article |
| id | doaj.art-1cc1d4eb99e04a54af53b54e438bc524 |
| institution | Directory Open Access Journal |
| issn | 1680-2993 2008-2363 |
| language | fas |
| last_indexed | 2024-04-13T15:33:58Z |
| publishDate | 2019-04-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
| spelling | doaj.art-1cc1d4eb99e04a54af53b54e438bc5242022-12-22T02:41:19ZfasMashhad University of Medical SciencesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān1680-29932008-23632019-04-01222738310.22038/ijogi.2019.1320513205The correlation of number of parity and bone mineral density (BMD) in women: A systematic review and meta-analysisMarzieh Saei Ghare Naz0Farzaneh Rashidi Fakari1Vida Ghasemi2Zahra Kiani3Giti Ozgoli4PhD Candidate of Reproductive Health, Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.PhD Candidate of Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.PhD Candidate of Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.PhD Candidate of Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Assistant Professor, Department of Midwifery and Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Introduction: Osteoporosis is a major health problem in women throughout the world. Based on the available evidence, delivery can play an important role in women's bone mineral density. Therefore, this study was performed with aim to determine the correlation between parity and bone mineral density through systematic review and. Methods: In this systematic review and meta-analysis study, for finding the related articles, the databases of PubMed, Scopus, Cochran library and Web of Science databases were searched without time limitation and with English language restriction by using of the keywords of Parity and Bone Mineral Density (BMD) or Bone Mineral Content or bone density. The adapted Newcastle-Ottawa Scale was used to assess the quality of the cross-sectional articles. Funnel plot and Egger's test was used for publication bias assessing. Q-test and I2 index were used for evaluation of heterogeneity. Fisher’s 𝑟-to-𝑧 transformation was calculated for the studies. Results: In this study, a total of 1336 papers were reviewed and 11 studies involving 5141 women were included in this meta-analysis. The decreasing trend in lumbar spine, femur and total hip BMD was observed in women with parity ≥5 compared to non-parity women. In nulliparous women, the mean of BMD in lumbar spine was (M:0.93 ,95%CI;0.75-1.11, Phetrogeneity <0.001), in femur (M:0.84 95%CI;0.60-1.09, Phetrogeneity <0.001) and in hip (M:0.86, 95%CI;0.84-0.89, Phetrogeneity =0.001). The mean of BMD in postmenopausal women was lower in lumbar, femur and hip. In African women, the mean of BMD in three sites were higher. There was no reverse moderate correlation between parity and lumbar BMD -0.22 (95% CI -0.14, -0.30) and hip BMD -0.21 (95% CI -0.12, -0.29). Conclusion: The mean BMD was higher in nulliparous women. There was inverse correlation between lumbar BMD and hip BMD with parity, but because of high heterogeneity in analyzed subgroups, performing cohort studies is recommended.https://ijogi.mums.ac.ir/article_13205_d4bae9a50987c290bdf6002338c04e81.pdfbone mineral densitymeta-analysisparity |
| spellingShingle | Marzieh Saei Ghare Naz Farzaneh Rashidi Fakari Vida Ghasemi Zahra Kiani Giti Ozgoli The correlation of number of parity and bone mineral density (BMD) in women: A systematic review and meta-analysis Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān bone mineral density meta-analysis parity |
| title | The correlation of number of parity and bone mineral density (BMD) in women: A systematic review and meta-analysis |
| title_full | The correlation of number of parity and bone mineral density (BMD) in women: A systematic review and meta-analysis |
| title_fullStr | The correlation of number of parity and bone mineral density (BMD) in women: A systematic review and meta-analysis |
| title_full_unstemmed | The correlation of number of parity and bone mineral density (BMD) in women: A systematic review and meta-analysis |
| title_short | The correlation of number of parity and bone mineral density (BMD) in women: A systematic review and meta-analysis |
| title_sort | correlation of number of parity and bone mineral density bmd in women a systematic review and meta analysis |
| topic | bone mineral density meta-analysis parity |
| url | https://ijogi.mums.ac.ir/article_13205_d4bae9a50987c290bdf6002338c04e81.pdf |
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