Enhancement of the Anticancer Ability of Natural Killer Cells through Allogeneic Mitochondrial Transfer

Enhancement of the Anticancer Ability of Natural Killer Cells through Allogeneic Mitochondrial Transfer

An in vitro culture period of at least 2 weeks is required to produce sufficient natural killer (NK) cells for immunotherapy, which are the key effectors in hematological malignancy treatment. Mitochondrial damage and fragmentation reduce the NK cell immune surveillance capacity. Thus, we hypothesiz...

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Bibliographic Details
Main Authors: Seong-Hoon Kim, Mi-Jin Kim, Mina Lim, Jihye Kim, Hyunmin Kim, Chang-Koo Yun, Yun-Joo Yoo, Youngjun Lee, Kyunghoon Min, Yong-Soo Choi
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
natural killer cells
immune cell therapy
mitochondria
mitochondrial transfer
anticancer immunotherapy
Online Access:https://www.mdpi.com/2072-6694/15/12/3225

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