Erythropoietin Non-hematopoietic Tissue Response and Regulation of Metabolism During Diet Induced Obesity

Erythropoietin Non-hematopoietic Tissue Response and Regulation of Metabolism During Diet Induced Obesity

Erythropoietin (EPO) receptor (EPOR) determines EPO response. High level EPOR on erythroid progenitor cells gives rise to EPO regulated production of red blood cells. Animal models provide evidence for EPO activity in non-hematopoietic tissue mediated by EPOR expression. Beyond erythropoiesis, EPO a...

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Bibliographic Details
Main Authors: Soumyadeep Dey, Jeeyoung Lee, Constance T. Noguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
erythropoietin
erythropoietin receptor
gender-specific
obesity
inflammation
hypothalamus
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.725734/full

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