Prevalence of metabolic syndrome in a Russian population: The Ural Eye and Medical Study and the Ural Very Old Study
Purpose: To examine prevalence and associated factors of the metabolic syndrome (MS) in populations in Russia. Methods: Two population-based studies (Ural Eye and Medical Study (UEMS), Ural Very Old Study (UVOS)) were conducted in rural and urban regions in Bashkortostan/Russia and included particip...
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-06-01
|
| Series: | Metabolism Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589936822000214 |
| _version_ | 1818470252428656640 |
|---|---|
| author | Mukharram M. Bikbov Gyulli M. Kazakbaeva Timur R. Gilmanshin Rinat M. Zainullin Ellina M. Iakupova Albina A. Fakhretdinova Azaliia M. Tuliakova Iuliia A. Rusakova Songhomitra Panda-Jonas Ildar F. Nuriev Artur F. Zaynetdinov Ainur A. Zinnatullin Inga I. Arslangareeva Ainur V. Gizzatov Natalia I. Bolshakova Kamilia R. Safiullina Jost B. Jonas |
| author_facet | Mukharram M. Bikbov Gyulli M. Kazakbaeva Timur R. Gilmanshin Rinat M. Zainullin Ellina M. Iakupova Albina A. Fakhretdinova Azaliia M. Tuliakova Iuliia A. Rusakova Songhomitra Panda-Jonas Ildar F. Nuriev Artur F. Zaynetdinov Ainur A. Zinnatullin Inga I. Arslangareeva Ainur V. Gizzatov Natalia I. Bolshakova Kamilia R. Safiullina Jost B. Jonas |
| author_sort | Mukharram M. Bikbov |
| collection | DOAJ |
| description | Purpose: To examine prevalence and associated factors of the metabolic syndrome (MS) in populations in Russia. Methods: Two population-based studies (Ural Eye and Medical Study (UEMS), Ural Very Old Study (UVOS)) were conducted in rural and urban regions in Bashkortostan/Russia and included participants aged 40+ years and 85+ years, respectively. Results: Out of 5895 UEMS participants, 1572 individuals had MS (prevalence:26.7%; 95% confidence interval (CI):25.5,27.8). The criteria of waist circumference, blood pressure, hyperglycemia, serum high-density lipoprotein concentration and serum triglyceride concentration were fulfilled by 4269 (72.4%; 95%CI:71.3,73.6), 3168 (53.7%; 95%CI:52.5,55.1), 1375 (23.3%; 95%CI:22.4,24.6), 712 (13.3%; 95%CI:12.4,14.2), and 1527 (28.6%; 95%CI:27.4,29.8) individuals, respectively. Higher MS prevalence was associated with older age (odds ratio (OR):1.03; 95%CI:1.02,1.04;P < 0.001), female sex (OR:1.93; 95%CI:1.51,2.47;P < 0.001), higher body height (OR:1.03; 95%CI:1.01,1.04;P < 0.001), Russian ethnicity (OR:1.38; 95%CI:1.13,1.70;P = 0.002), lower ankle-brachial index (OR:0.19; 95%CI:0.11,0.30;P < 0.001), higher prevalence of lower backache (OR:1.29; 95%CI:1.08,1.52;P = 0.004), cardiovascular disease (OR:2.32; 95%CI:1.92,2.78;P < 0.001) and thyroid disease (OR:1.41; 95%CI:1.04,1.92;P = 0.03), lower international normalized ratio (OR:0.55; 95%CI:0.32,0.95;P = 0.03), lower prevalence of current smoking (OR:0.67; 95%CI:0.50,0.89;P = 0.006), and higher prevalence of alcohol consumption (OR:1.35; 95%CI:1.11,1.64;P = 0.003). Out of 1124 UVOS participants (age:88.2 ± 2.7 years; range:85–100 years), MS was present in 485 individuals (prevalence:43.1%; 95%CI:40.3,46.1). The criteria of waist circumference, blood pressure, hyperglycemia, serum high-density lipoprotein concentration and serum triglyceride concentration were fulfilled by 853 (75.9%; 95%CI:73.4,78.4), 1057 (94.0%; 95%CI:92.7,95.4), 320 (26.9%; 95%CI:24.3,29.5), 525 (46.7%; 95%CI:43.8,49.6), and 337 (30.0%; 95%CI:27.3,32.7, individuals, respectively. Higher MS prevalence was associated with female sex (OR:2.30; 95%CI:1.72,3.09;P < 0.001) and higher serum concentration of aspartate transaminase (OR:1.02; 95%CI:1.01,1.03;P = 0.007). Conclusions: MS is common in Russia, increases with age up to about 70 years and then plateaus, is more common in women, and differs in its associated factors between middle-aged and very old populations. |
| first_indexed | 2024-04-13T21:35:01Z |
| format | Article |
| id | doaj.art-1cc680996b394edd9362b73281986d80 |
| institution | Directory Open Access Journal |
| issn | 2589-9368 |
| language | English |
| last_indexed | 2024-04-13T21:35:01Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Metabolism Open |
| spelling | doaj.art-1cc680996b394edd9362b73281986d802022-12-22T02:29:00ZengElsevierMetabolism Open2589-93682022-06-0114100183Prevalence of metabolic syndrome in a Russian population: The Ural Eye and Medical Study and the Ural Very Old StudyMukharram M. Bikbov0Gyulli M. Kazakbaeva1Timur R. Gilmanshin2Rinat M. Zainullin3Ellina M. Iakupova4Albina A. Fakhretdinova5Azaliia M. Tuliakova6Iuliia A. Rusakova7Songhomitra Panda-Jonas8Ildar F. Nuriev9Artur F. Zaynetdinov10Ainur A. Zinnatullin11Inga I. Arslangareeva12Ainur V. Gizzatov13Natalia I. Bolshakova14Kamilia R. Safiullina15Jost B. Jonas16Ufa Eye Research Institute, Ufa, Bashkortostan, Russia; Corresponding author. Ufa Eye Research Institute, 90 Pushkin Street, Ufa, 450077, Bashkortostan, Russia.Ufa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaPrivatpraxis Prof Jonas und Dr Panda-Jonas, Heidelberg, GermanyUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaUfa Eye Research Institute, Ufa, Bashkortostan, RussiaPrivatpraxis Prof Jonas und Dr Panda-Jonas, Heidelberg, Germany; Department of Ophthalmology, Medical Faculty Mannheim. Heidelberg University, Mannheim, Germany; Institute of Molecular and Clinical Ophthalmology Basel, Switzerland; Corresponding author. Department of Ophthalmology, Medical Faculty Mannheim, Theodor-Kutzerufer 1, 68167, Mannheim, Germany.Purpose: To examine prevalence and associated factors of the metabolic syndrome (MS) in populations in Russia. Methods: Two population-based studies (Ural Eye and Medical Study (UEMS), Ural Very Old Study (UVOS)) were conducted in rural and urban regions in Bashkortostan/Russia and included participants aged 40+ years and 85+ years, respectively. Results: Out of 5895 UEMS participants, 1572 individuals had MS (prevalence:26.7%; 95% confidence interval (CI):25.5,27.8). The criteria of waist circumference, blood pressure, hyperglycemia, serum high-density lipoprotein concentration and serum triglyceride concentration were fulfilled by 4269 (72.4%; 95%CI:71.3,73.6), 3168 (53.7%; 95%CI:52.5,55.1), 1375 (23.3%; 95%CI:22.4,24.6), 712 (13.3%; 95%CI:12.4,14.2), and 1527 (28.6%; 95%CI:27.4,29.8) individuals, respectively. Higher MS prevalence was associated with older age (odds ratio (OR):1.03; 95%CI:1.02,1.04;P < 0.001), female sex (OR:1.93; 95%CI:1.51,2.47;P < 0.001), higher body height (OR:1.03; 95%CI:1.01,1.04;P < 0.001), Russian ethnicity (OR:1.38; 95%CI:1.13,1.70;P = 0.002), lower ankle-brachial index (OR:0.19; 95%CI:0.11,0.30;P < 0.001), higher prevalence of lower backache (OR:1.29; 95%CI:1.08,1.52;P = 0.004), cardiovascular disease (OR:2.32; 95%CI:1.92,2.78;P < 0.001) and thyroid disease (OR:1.41; 95%CI:1.04,1.92;P = 0.03), lower international normalized ratio (OR:0.55; 95%CI:0.32,0.95;P = 0.03), lower prevalence of current smoking (OR:0.67; 95%CI:0.50,0.89;P = 0.006), and higher prevalence of alcohol consumption (OR:1.35; 95%CI:1.11,1.64;P = 0.003). Out of 1124 UVOS participants (age:88.2 ± 2.7 years; range:85–100 years), MS was present in 485 individuals (prevalence:43.1%; 95%CI:40.3,46.1). The criteria of waist circumference, blood pressure, hyperglycemia, serum high-density lipoprotein concentration and serum triglyceride concentration were fulfilled by 853 (75.9%; 95%CI:73.4,78.4), 1057 (94.0%; 95%CI:92.7,95.4), 320 (26.9%; 95%CI:24.3,29.5), 525 (46.7%; 95%CI:43.8,49.6), and 337 (30.0%; 95%CI:27.3,32.7, individuals, respectively. Higher MS prevalence was associated with female sex (OR:2.30; 95%CI:1.72,3.09;P < 0.001) and higher serum concentration of aspartate transaminase (OR:1.02; 95%CI:1.01,1.03;P = 0.007). Conclusions: MS is common in Russia, increases with age up to about 70 years and then plateaus, is more common in women, and differs in its associated factors between middle-aged and very old populations.http://www.sciencedirect.com/science/article/pii/S2589936822000214Metabolic syndromeHyperlipidemiaArterial hypertensionHyperglycemiaPopulation-based studyRussia |
| spellingShingle | Mukharram M. Bikbov Gyulli M. Kazakbaeva Timur R. Gilmanshin Rinat M. Zainullin Ellina M. Iakupova Albina A. Fakhretdinova Azaliia M. Tuliakova Iuliia A. Rusakova Songhomitra Panda-Jonas Ildar F. Nuriev Artur F. Zaynetdinov Ainur A. Zinnatullin Inga I. Arslangareeva Ainur V. Gizzatov Natalia I. Bolshakova Kamilia R. Safiullina Jost B. Jonas Prevalence of metabolic syndrome in a Russian population: The Ural Eye and Medical Study and the Ural Very Old Study Metabolism Open Metabolic syndrome Hyperlipidemia Arterial hypertension Hyperglycemia Population-based study Russia |
| title | Prevalence of metabolic syndrome in a Russian population: The Ural Eye and Medical Study and the Ural Very Old Study |
| title_full | Prevalence of metabolic syndrome in a Russian population: The Ural Eye and Medical Study and the Ural Very Old Study |
| title_fullStr | Prevalence of metabolic syndrome in a Russian population: The Ural Eye and Medical Study and the Ural Very Old Study |
| title_full_unstemmed | Prevalence of metabolic syndrome in a Russian population: The Ural Eye and Medical Study and the Ural Very Old Study |
| title_short | Prevalence of metabolic syndrome in a Russian population: The Ural Eye and Medical Study and the Ural Very Old Study |
| title_sort | prevalence of metabolic syndrome in a russian population the ural eye and medical study and the ural very old study |
| topic | Metabolic syndrome Hyperlipidemia Arterial hypertension Hyperglycemia Population-based study Russia |
| url | http://www.sciencedirect.com/science/article/pii/S2589936822000214 |
| work_keys_str_mv | AT mukharrammbikbov prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT gyullimkazakbaeva prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT timurrgilmanshin prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT rinatmzainullin prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT ellinamiakupova prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT albinaafakhretdinova prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT azaliiamtuliakova prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT iuliiaarusakova prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT songhomitrapandajonas prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT ildarfnuriev prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT arturfzaynetdinov prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT ainurazinnatullin prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT ingaiarslangareeva prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT ainurvgizzatov prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT nataliaibolshakova prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT kamiliarsafiullina prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy AT jostbjonas prevalenceofmetabolicsyndromeinarussianpopulationtheuraleyeandmedicalstudyandtheuralveryoldstudy |