Predictors for the Bronchiolitis Obliterans Syndrome in Lung Transplant Patient
Lung transplantation is the ultimate treatment of end-stage lung disease. After transplantation, the 1-year survival rate is 80%, while the 5-year survival rates remaines at around 50% mainly due to bronchiolitis obliterans syndrome (BOS). BOS is regarded as a fibrosing process in the small airways...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
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Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2020-06-01
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| Series: | Chinese Journal of Lung Cancer |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.03 |
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| author | Sijia YANG Abudumailamu ABUDUWUFUER Wang LV Feichao BAO Jian HU |
| author_facet | Sijia YANG Abudumailamu ABUDUWUFUER Wang LV Feichao BAO Jian HU |
| author_sort | Sijia YANG |
| collection | DOAJ |
| description | Lung transplantation is the ultimate treatment of end-stage lung disease. After transplantation, the 1-year survival rate is 80%, while the 5-year survival rates remaines at around 50% mainly due to bronchiolitis obliterans syndrome (BOS). BOS is regarded as a fibrosing process in the small airways leading to irreversible airway obstruction. A lot of factors are involved in the development of BOS, such as Ischemia/reperfusion injury, infections, oxidative stress, and acute rejection, etc. Studies have shown that early diagnosis of BOS may improve outcome. It is valuable for the long-term survival of lung transplantation to find out several predictors for the BOS. This article reviews the current state of knowledge on predictors for BOS. |
| first_indexed | 2024-12-23T04:24:25Z |
| format | Article |
| id | doaj.art-1cc74f05b53746d5a3a70220b1b6866f |
| institution | Directory Open Access Journal |
| issn | 1009-3419 1999-6187 |
| language | zho |
| last_indexed | 2024-12-23T04:24:25Z |
| publishDate | 2020-06-01 |
| publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
| record_format | Article |
| series | Chinese Journal of Lung Cancer |
| spelling | doaj.art-1cc74f05b53746d5a3a70220b1b6866f2022-12-21T18:00:09ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872020-06-0123649650210.3779/j.issn.1009-3419.2020.101.03Predictors for the Bronchiolitis Obliterans Syndrome in Lung Transplant PatientSijia YANG0Abudumailamu ABUDUWUFUER1Wang LV2Feichao BAO3Jian HU4The First Affiliated Hospital, Collage of Medicine, Zhejiang University, Hangzhou 310003, ChinaThe First Affiliated Hospital, Collage of Medicine, Zhejiang University, Hangzhou 310003, ChinaThe First Affiliated Hospital, Collage of Medicine, Zhejiang University, Hangzhou 310003, ChinaThe First Affiliated Hospital, Collage of Medicine, Zhejiang University, Hangzhou 310003, ChinaThe First Affiliated Hospital, Collage of Medicine, Zhejiang University, Hangzhou 310003, ChinaLung transplantation is the ultimate treatment of end-stage lung disease. After transplantation, the 1-year survival rate is 80%, while the 5-year survival rates remaines at around 50% mainly due to bronchiolitis obliterans syndrome (BOS). BOS is regarded as a fibrosing process in the small airways leading to irreversible airway obstruction. A lot of factors are involved in the development of BOS, such as Ischemia/reperfusion injury, infections, oxidative stress, and acute rejection, etc. Studies have shown that early diagnosis of BOS may improve outcome. It is valuable for the long-term survival of lung transplantation to find out several predictors for the BOS. This article reviews the current state of knowledge on predictors for BOS.http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.03lung transplantationbronchiolitis obliterans syndromepredictor |
| spellingShingle | Sijia YANG Abudumailamu ABUDUWUFUER Wang LV Feichao BAO Jian HU Predictors for the Bronchiolitis Obliterans Syndrome in Lung Transplant Patient Chinese Journal of Lung Cancer lung transplantation bronchiolitis obliterans syndrome predictor |
| title | Predictors for the Bronchiolitis Obliterans Syndrome in Lung Transplant Patient |
| title_full | Predictors for the Bronchiolitis Obliterans Syndrome in Lung Transplant Patient |
| title_fullStr | Predictors for the Bronchiolitis Obliterans Syndrome in Lung Transplant Patient |
| title_full_unstemmed | Predictors for the Bronchiolitis Obliterans Syndrome in Lung Transplant Patient |
| title_short | Predictors for the Bronchiolitis Obliterans Syndrome in Lung Transplant Patient |
| title_sort | predictors for the bronchiolitis obliterans syndrome in lung transplant patient |
| topic | lung transplantation bronchiolitis obliterans syndrome predictor |
| url | http://dx.doi.org/10.3779/j.issn.1009-3419.2020.101.03 |
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