Comparison of different methods to assess tacrolimus concentration intra-patient variability as potential marker of medication non-adherence

Comparison of different methods to assess tacrolimus concentration intra-patient variability as potential marker of medication non-adherence

Background and objective: Non-adherence to tacrolimus commonly manifests as low drug concentrations and/or high intra-patient variability (IPV) of concentrations across multiple measurements. We aimed to compare several methods of tacrolimus IPV calculation and evaluate how well each reflects blood...

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Bibliographic Details
Main Authors:	Barbora Kostalova, Katerina Mala-Ladova, Sylvie Dusilova Sulkova, Kris Denhaerynck, Sabina De Geest, Josef Maly
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Series:	Frontiers in Pharmacology
Subjects:	immunosuppression kidney transplantation intra-patient variability medication adherence tacrolimus immunosuppression tacrolimus
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.973564/full

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