The Impact of Activin A on Fetal Gonocytes: Chronic Versus Acute Exposure Outcomes

Activin A, a TGFβ superfamily member, is important for normal testis development through its actions on Sertoli cell development. Our analyses of altered activin A mouse models indicated gonocyte abnormalities, implicating activin A as a key determinant of early germline formation. Whether it acts d...

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Bibliographic Details
Main Authors: Sarah C. Moody, Penny A. F. Whiley, Patrick S. Western, Kate L. Loveland
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.896747/full