Tachykinins: Neuropeptides That Are Ancient, Diverse, Widespread and Functionally Pleiotropic

Tachykinins: Neuropeptides That Are Ancient, Diverse, Widespread and Functionally Pleiotropic

Tachykinins (TKs) are ancient neuropeptides present throughout the bilaterians and are, with some exceptions, characterized by a conserved FX1GX2Ramide carboxy terminus among protostomes and FXGLMamide in deuterostomes. The best-known TK is the vertebrate substance P, which in mammals, together with...

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Bibliographic Details
Main Authors: Dick R. Nässel, Meet Zandawala, Tsuyoshi Kawada, Honoo Satake
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neuroscience
Subjects:
substance P
neurokinin
neurokinin receptor
natalisin
G protein-coupled receptor
co-transmission
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01262/full

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