Investigating functional brain connectivity patterns associated with two hypnotic states
While there’s been clinical success and growing research interest in hypnosis, neurobiological underpinnings induced by hypnosis remain unclear. In this fMRI study (which is part of a larger hypnosis project) with 50 hypnosis-experienced participants, we analyzed neural and physiological responses d...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-12-01
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| Series: | Frontiers in Human Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnhum.2023.1286336/full |
| _version_ | 1797386223398944768 |
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| author | Nuno M. P. de Matos Philipp Staempfli Erich Seifritz Katrin Preller Mike Bruegger |
| author_facet | Nuno M. P. de Matos Philipp Staempfli Erich Seifritz Katrin Preller Mike Bruegger |
| author_sort | Nuno M. P. de Matos |
| collection | DOAJ |
| description | While there’s been clinical success and growing research interest in hypnosis, neurobiological underpinnings induced by hypnosis remain unclear. In this fMRI study (which is part of a larger hypnosis project) with 50 hypnosis-experienced participants, we analyzed neural and physiological responses during two hypnosis states, comparing them to non-hypnotic control conditions and to each other. An unbiased whole-brain analysis (multi-voxel- pattern analysis, MVPA), pinpointed key neural hubs in parieto-occipital-temporal areas, cuneal/precuneal and occipital cortices, lingual gyri, and the occipital pole. Comparing directly both hypnotic states revealed depth-dependent connectivity changes, notably in left superior temporal/supramarginal gyri, cuneus, planum temporale, and lingual gyri. Multi-voxel- pattern analysis (MVPA) based seeds were implemented in a seed-to-voxel analysis unveiling region-specific increases and decreases in functional connectivity patterns. Physiologically, the respiration rate significantly slowed during hypnosis. Summarized, these findings foster fresh insights into hypnosis-induced functional connectivity changes and illuminate further knowledge related with the neurobiology of altered consciousness. |
| first_indexed | 2024-03-08T22:05:56Z |
| format | Article |
| id | doaj.art-1ccee31589944befb13e817acfb8d6a0 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-03-08T22:05:56Z |
| publishDate | 2023-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-1ccee31589944befb13e817acfb8d6a02023-12-19T09:03:55ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612023-12-011710.3389/fnhum.2023.12863361286336Investigating functional brain connectivity patterns associated with two hypnotic statesNuno M. P. de Matos0Philipp Staempfli1Erich Seifritz2Katrin Preller3Mike Bruegger4Clinic of Cranio-Maxillofacial and Oral Surgery, Center of Dental Medicine, University of Zurich, Zurich, SwitzerlandMR-Center of the Department of Psychiatry, Psychotherapy and Psychosomatics, Department of Child and Adolescent Psychiatry, Psychiatric Hospital, University of Zurich, Zurich, SwitzerlandDepartment of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, SwitzerlandDepartment of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, SwitzerlandClinic of Cranio-Maxillofacial and Oral Surgery, Center of Dental Medicine, University of Zurich, Zurich, SwitzerlandWhile there’s been clinical success and growing research interest in hypnosis, neurobiological underpinnings induced by hypnosis remain unclear. In this fMRI study (which is part of a larger hypnosis project) with 50 hypnosis-experienced participants, we analyzed neural and physiological responses during two hypnosis states, comparing them to non-hypnotic control conditions and to each other. An unbiased whole-brain analysis (multi-voxel- pattern analysis, MVPA), pinpointed key neural hubs in parieto-occipital-temporal areas, cuneal/precuneal and occipital cortices, lingual gyri, and the occipital pole. Comparing directly both hypnotic states revealed depth-dependent connectivity changes, notably in left superior temporal/supramarginal gyri, cuneus, planum temporale, and lingual gyri. Multi-voxel- pattern analysis (MVPA) based seeds were implemented in a seed-to-voxel analysis unveiling region-specific increases and decreases in functional connectivity patterns. Physiologically, the respiration rate significantly slowed during hypnosis. Summarized, these findings foster fresh insights into hypnosis-induced functional connectivity changes and illuminate further knowledge related with the neurobiology of altered consciousness.https://www.frontiersin.org/articles/10.3389/fnhum.2023.1286336/fulldistinct hypnosis statesfunctional connectivitymulti-voxel-pattern-analysisphysiological parameterrespirationposterior hot zone |
| spellingShingle | Nuno M. P. de Matos Philipp Staempfli Erich Seifritz Katrin Preller Mike Bruegger Investigating functional brain connectivity patterns associated with two hypnotic states Frontiers in Human Neuroscience distinct hypnosis states functional connectivity multi-voxel-pattern-analysis physiological parameter respiration posterior hot zone |
| title | Investigating functional brain connectivity patterns associated with two hypnotic states |
| title_full | Investigating functional brain connectivity patterns associated with two hypnotic states |
| title_fullStr | Investigating functional brain connectivity patterns associated with two hypnotic states |
| title_full_unstemmed | Investigating functional brain connectivity patterns associated with two hypnotic states |
| title_short | Investigating functional brain connectivity patterns associated with two hypnotic states |
| title_sort | investigating functional brain connectivity patterns associated with two hypnotic states |
| topic | distinct hypnosis states functional connectivity multi-voxel-pattern-analysis physiological parameter respiration posterior hot zone |
| url | https://www.frontiersin.org/articles/10.3389/fnhum.2023.1286336/full |
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