Serological evidence of possible Borrelia afzelii lyme disease in Greece

Suggestions that Lyme disease exists in Greece remain controversial and no study to date has definitively identified the presence of a Borrelia species that infects humans. We examined patients throughout Greece suspected for Lyme disease by enzyme-linked immunosorbent assay (ELISA) and by western b...

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Main Authors: I. Karageorgou, M. Koutantou, I. Papadogiannaki, A. Voulgari-Kokota, S. Makka, E. Angelakis
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:New Microbes and New Infections
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2052297522000300
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author I. Karageorgou
M. Koutantou
I. Papadogiannaki
A. Voulgari-Kokota
S. Makka
E. Angelakis
author_facet I. Karageorgou
M. Koutantou
I. Papadogiannaki
A. Voulgari-Kokota
S. Makka
E. Angelakis
author_sort I. Karageorgou
collection DOAJ
description Suggestions that Lyme disease exists in Greece remain controversial and no study to date has definitively identified the presence of a Borrelia species that infects humans. We examined patients throughout Greece suspected for Lyme disease by enzyme-linked immunosorbent assay (ELISA) and by western blotting for Borrelia burgdorferi sensu lato species. We found one patient positive for Borrelia burgdorferi and two patients positive for Borrelia afzelii specific IgG antibodies. Both B. afzelii patients were suffering by neurological manifestations and had never traveled abroad. We provide serological evidence of two autochthonous Lyme disease cases in Greece, possibly caused by B. afzelii.
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spelling doaj.art-1cd77b9cad864a169dae1c75a44e91052022-12-22T02:28:03ZengElsevierNew Microbes and New Infections2052-29752022-03-0146100978Serological evidence of possible Borrelia afzelii lyme disease in GreeceI. Karageorgou0M. Koutantou1I. Papadogiannaki2A. Voulgari-Kokota3S. Makka4E. Angelakis5Diagnostic Department and Public Health Laboratories, Hellenic Pasteur Institute, Athens, GreeceDiagnostic Department and Public Health Laboratories, Hellenic Pasteur Institute, Athens, GreeceDiagnostic Department and Public Health Laboratories, Hellenic Pasteur Institute, Athens, GreeceDiagnostic Department and Public Health Laboratories, Hellenic Pasteur Institute, Athens, GreeceDiagnostic Department and Public Health Laboratories, Hellenic Pasteur Institute, Athens, GreeceCorresponding author: E. Angelakis; Diagnostic Department and Public Health Laboratories, Hellenic Pasteur Institute, Athens, GreeceSuggestions that Lyme disease exists in Greece remain controversial and no study to date has definitively identified the presence of a Borrelia species that infects humans. We examined patients throughout Greece suspected for Lyme disease by enzyme-linked immunosorbent assay (ELISA) and by western blotting for Borrelia burgdorferi sensu lato species. We found one patient positive for Borrelia burgdorferi and two patients positive for Borrelia afzelii specific IgG antibodies. Both B. afzelii patients were suffering by neurological manifestations and had never traveled abroad. We provide serological evidence of two autochthonous Lyme disease cases in Greece, possibly caused by B. afzelii.http://www.sciencedirect.com/science/article/pii/S2052297522000300Borrelia afzeliiGreeceLyme borrelialyme disease
spellingShingle I. Karageorgou
M. Koutantou
I. Papadogiannaki
A. Voulgari-Kokota
S. Makka
E. Angelakis
Serological evidence of possible Borrelia afzelii lyme disease in Greece
New Microbes and New Infections
Borrelia afzelii
Greece
Lyme borrelia
lyme disease
title Serological evidence of possible Borrelia afzelii lyme disease in Greece
title_full Serological evidence of possible Borrelia afzelii lyme disease in Greece
title_fullStr Serological evidence of possible Borrelia afzelii lyme disease in Greece
title_full_unstemmed Serological evidence of possible Borrelia afzelii lyme disease in Greece
title_short Serological evidence of possible Borrelia afzelii lyme disease in Greece
title_sort serological evidence of possible borrelia afzelii lyme disease in greece
topic Borrelia afzelii
Greece
Lyme borrelia
lyme disease
url http://www.sciencedirect.com/science/article/pii/S2052297522000300
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