Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist 6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-type virus. Of 227 vaccinated healthcare workers tested, only 2 experienced outpatient symptomatic breakthrough inf...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2022-04-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/28/4/21-2037_article |
| _version_ | 1818315339634573312 |
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| author | Eric D. Laing Carol D. Weiss Emily C. Samuels Si’Ana A. Coggins Wei Wang Richard Wang Russell Vassell Spencer L. Sterling Marana S. Tso Tonia Conner Emilie Goguet Matthew Moser Belinda M. Jackson-Thompson Luca Illinik Julian Davies Orlando Ortega Edward Parmelee Monique Hollis-Perry Santina E. Maiolatesi Gregory Wang Kathleen F. Ramsey Anatalio E. Reyes Yolanda Alcorta Mimi A. Wong Alyssa R. Lindrose Christopher A. Duplessis David R. Tribble Allison M.W. Malloy Timothy H. Burgess Simon D. Pollett Cara H. Olsen Christopher C. Broder Edward Mitre |
| author_facet | Eric D. Laing Carol D. Weiss Emily C. Samuels Si’Ana A. Coggins Wei Wang Richard Wang Russell Vassell Spencer L. Sterling Marana S. Tso Tonia Conner Emilie Goguet Matthew Moser Belinda M. Jackson-Thompson Luca Illinik Julian Davies Orlando Ortega Edward Parmelee Monique Hollis-Perry Santina E. Maiolatesi Gregory Wang Kathleen F. Ramsey Anatalio E. Reyes Yolanda Alcorta Mimi A. Wong Alyssa R. Lindrose Christopher A. Duplessis David R. Tribble Allison M.W. Malloy Timothy H. Burgess Simon D. Pollett Cara H. Olsen Christopher C. Broder Edward Mitre |
| author_sort | Eric D. Laing |
| collection | DOAJ |
| description |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist 6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-type virus. Of 227 vaccinated healthcare workers tested, only 2 experienced outpatient symptomatic breakthrough infections, despite 59/227 exhibiting serologic evidence of SARS-CoV-2 infection, defined as presence of nucleocapsid protein antibodies.
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| first_indexed | 2024-12-13T09:03:58Z |
| format | Article |
| id | doaj.art-1cd8ef6923d34344817f8a6b6fe3a799 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-13T09:03:58Z |
| publishDate | 2022-04-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-1cd8ef6923d34344817f8a6b6fe3a7992022-12-21T23:53:06ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592022-04-0128482883210.3201/eid2804.212037Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare WorkersEric D. LaingCarol D. WeissEmily C. SamuelsSi’Ana A. CogginsWei WangRichard WangRussell VassellSpencer L. SterlingMarana S. TsoTonia ConnerEmilie GoguetMatthew MoserBelinda M. Jackson-ThompsonLuca IllinikJulian DaviesOrlando OrtegaEdward ParmeleeMonique Hollis-PerrySantina E. MaiolatesiGregory WangKathleen F. RamseyAnatalio E. ReyesYolanda AlcortaMimi A. WongAlyssa R. LindroseChristopher A. DuplessisDavid R. TribbleAllison M.W. MalloyTimothy H. BurgessSimon D. PollettCara H. OlsenChristopher C. BroderEdward Mitre Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies decay but persist 6 months postvaccination; lower levels of neutralizing titers persist against Delta than wild-type virus. Of 227 vaccinated healthcare workers tested, only 2 experienced outpatient symptomatic breakthrough infections, despite 59/227 exhibiting serologic evidence of SARS-CoV-2 infection, defined as presence of nucleocapsid protein antibodies. https://wwwnc.cdc.gov/eid/article/28/4/21-2037_articleCOVID-19coronavirus diseaseSARS-CoV-2severe acute respiratory syndrome coronavirus 2virusesrespiratory infections |
| spellingShingle | Eric D. Laing Carol D. Weiss Emily C. Samuels Si’Ana A. Coggins Wei Wang Richard Wang Russell Vassell Spencer L. Sterling Marana S. Tso Tonia Conner Emilie Goguet Matthew Moser Belinda M. Jackson-Thompson Luca Illinik Julian Davies Orlando Ortega Edward Parmelee Monique Hollis-Perry Santina E. Maiolatesi Gregory Wang Kathleen F. Ramsey Anatalio E. Reyes Yolanda Alcorta Mimi A. Wong Alyssa R. Lindrose Christopher A. Duplessis David R. Tribble Allison M.W. Malloy Timothy H. Burgess Simon D. Pollett Cara H. Olsen Christopher C. Broder Edward Mitre Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers Emerging Infectious Diseases COVID-19 coronavirus disease SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 viruses respiratory infections |
| title | Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers |
| title_full | Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers |
| title_fullStr | Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers |
| title_full_unstemmed | Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers |
| title_short | Durability of Antibody Response and Frequency of SARS-CoV-2 Infection 6 Months after COVID-19 Vaccination in Healthcare Workers |
| title_sort | durability of antibody response and frequency of sars cov 2 infection 6 months after covid 19 vaccination in healthcare workers |
| topic | COVID-19 coronavirus disease SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 viruses respiratory infections |
| url | https://wwwnc.cdc.gov/eid/article/28/4/21-2037_article |
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