Diversity of Salmonella serotypes from humans, food, domestic animals and wildlife in New South Wales, Australia
Abstract Background Salmonella is an important human pathogen in Australia and annual case rates continue to increase. In addition to foodborne exposures, cases have been associated with animal and contaminated environment contact. However, routine surveillance in Australia has tended to focus on hu...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-12-01
|
| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12879-018-3563-1 |
| _version_ | 1818879948752945152 |
|---|---|
| author | Kelly M. J. Simpson Grant A. Hill-Cawthorne Michael P. Ward Siobhan M. Mor |
| author_facet | Kelly M. J. Simpson Grant A. Hill-Cawthorne Michael P. Ward Siobhan M. Mor |
| author_sort | Kelly M. J. Simpson |
| collection | DOAJ |
| description | Abstract Background Salmonella is an important human pathogen in Australia and annual case rates continue to increase. In addition to foodborne exposures, cases have been associated with animal and contaminated environment contact. However, routine surveillance in Australia has tended to focus on humans and food, with no reported attempts to collate and compare Salmonella data from a wider range of potential sources of exposure. Methods Salmonella data from humans, food, animals and environments were collated from a range of surveillance and diagnostic sources in New South Wales (NSW). Data were categorised to reflect one of 29 sample origins. Serotype diversity was described for each category, and the distribution of serotypes commonly isolated from humans was examined for each sample origin. The distribution of serotypes along the livestock-food-human continuum and at the companion animal-wildlife interface was also examined. Results In total, 49,872 Salmonella isolates were included in this analysis, comprising 325 serotypes. The vast majority of these isolates were from humans (n = 38,106). Overall S. Typhimurium was the most frequently isolated serotype and was isolated from all sample categories except natural environment and game meat. S. Enteriditis was not isolated from any livestock animal, however sporadic cases were documented in food, companion animals and a reptile. Many serotypes that were frequently isolated from livestock animals and associated food products were only rarely isolated from humans. In addition, a number of key human serotypes were only sporadically isolated from livestock and food products, suggesting alternative sources of infection. In particular, S. Paratyphi B Java and S. Wangata were more often isolated from wild animals. Finally, there was some overlap between serotypes in companion animals and wildlife, with cats in particular having a large number of serotypes in common with wild birds. Conclusions This is the most comprehensive description of Salmonella data from humans, food, livestock, wildlife, companion animals and various environments in Australia reported to date. Results confirm that livestock and food are important sources of salmonellosis in humans but that alternative sources - such as contact with wildlife and environments - warrant further investigation. Surveillance in NSW is largely human-focussed: major knowledge gaps exist regarding the diversity and frequency of serotypes in animals. More systematic surveillance of domestic animals and wildlife is needed to inform targeted control strategies and quantitative source attribution modelling in this state. |
| first_indexed | 2024-12-19T14:38:11Z |
| format | Article |
| id | doaj.art-1cd98fca838a42bd9287be70fbd9f740 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-19T14:38:11Z |
| publishDate | 2018-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-1cd98fca838a42bd9287be70fbd9f7402022-12-21T20:17:10ZengBMCBMC Infectious Diseases1471-23342018-12-0118111110.1186/s12879-018-3563-1Diversity of Salmonella serotypes from humans, food, domestic animals and wildlife in New South Wales, AustraliaKelly M. J. Simpson0Grant A. Hill-Cawthorne1Michael P. Ward2Siobhan M. Mor3School of Veterinary Science, Faculty of Science, University of SydneySchool of Public Health, University of SydneySchool of Veterinary Science, Faculty of Science, University of SydneySchool of Veterinary Science, Faculty of Science, University of SydneyAbstract Background Salmonella is an important human pathogen in Australia and annual case rates continue to increase. In addition to foodborne exposures, cases have been associated with animal and contaminated environment contact. However, routine surveillance in Australia has tended to focus on humans and food, with no reported attempts to collate and compare Salmonella data from a wider range of potential sources of exposure. Methods Salmonella data from humans, food, animals and environments were collated from a range of surveillance and diagnostic sources in New South Wales (NSW). Data were categorised to reflect one of 29 sample origins. Serotype diversity was described for each category, and the distribution of serotypes commonly isolated from humans was examined for each sample origin. The distribution of serotypes along the livestock-food-human continuum and at the companion animal-wildlife interface was also examined. Results In total, 49,872 Salmonella isolates were included in this analysis, comprising 325 serotypes. The vast majority of these isolates were from humans (n = 38,106). Overall S. Typhimurium was the most frequently isolated serotype and was isolated from all sample categories except natural environment and game meat. S. Enteriditis was not isolated from any livestock animal, however sporadic cases were documented in food, companion animals and a reptile. Many serotypes that were frequently isolated from livestock animals and associated food products were only rarely isolated from humans. In addition, a number of key human serotypes were only sporadically isolated from livestock and food products, suggesting alternative sources of infection. In particular, S. Paratyphi B Java and S. Wangata were more often isolated from wild animals. Finally, there was some overlap between serotypes in companion animals and wildlife, with cats in particular having a large number of serotypes in common with wild birds. Conclusions This is the most comprehensive description of Salmonella data from humans, food, livestock, wildlife, companion animals and various environments in Australia reported to date. Results confirm that livestock and food are important sources of salmonellosis in humans but that alternative sources - such as contact with wildlife and environments - warrant further investigation. Surveillance in NSW is largely human-focussed: major knowledge gaps exist regarding the diversity and frequency of serotypes in animals. More systematic surveillance of domestic animals and wildlife is needed to inform targeted control strategies and quantitative source attribution modelling in this state.http://link.springer.com/article/10.1186/s12879-018-3563-1SalmonellaOne HealthWildlifeCompanion animalsLivestockFood |
| spellingShingle | Kelly M. J. Simpson Grant A. Hill-Cawthorne Michael P. Ward Siobhan M. Mor Diversity of Salmonella serotypes from humans, food, domestic animals and wildlife in New South Wales, Australia BMC Infectious Diseases Salmonella One Health Wildlife Companion animals Livestock Food |
| title | Diversity of Salmonella serotypes from humans, food, domestic animals and wildlife in New South Wales, Australia |
| title_full | Diversity of Salmonella serotypes from humans, food, domestic animals and wildlife in New South Wales, Australia |
| title_fullStr | Diversity of Salmonella serotypes from humans, food, domestic animals and wildlife in New South Wales, Australia |
| title_full_unstemmed | Diversity of Salmonella serotypes from humans, food, domestic animals and wildlife in New South Wales, Australia |
| title_short | Diversity of Salmonella serotypes from humans, food, domestic animals and wildlife in New South Wales, Australia |
| title_sort | diversity of salmonella serotypes from humans food domestic animals and wildlife in new south wales australia |
| topic | Salmonella One Health Wildlife Companion animals Livestock Food |
| url | http://link.springer.com/article/10.1186/s12879-018-3563-1 |
| work_keys_str_mv | AT kellymjsimpson diversityofsalmonellaserotypesfromhumansfooddomesticanimalsandwildlifeinnewsouthwalesaustralia AT grantahillcawthorne diversityofsalmonellaserotypesfromhumansfooddomesticanimalsandwildlifeinnewsouthwalesaustralia AT michaelpward diversityofsalmonellaserotypesfromhumansfooddomesticanimalsandwildlifeinnewsouthwalesaustralia AT siobhanmmor diversityofsalmonellaserotypesfromhumansfooddomesticanimalsandwildlifeinnewsouthwalesaustralia |