Recent Microfluidic Innovations for Sperm Sorting
Sperm selection is a clinical need for guided fertilization in men with low-quality semen. In this regard, microfluidics can provide an enabling platform for the precise manipulation and separation of high-quality sperm cells through applying various stimuli, including chemical agents, mechanical fo...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Chemosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9040/9/6/126 |
| _version_ | 1797531705447284736 |
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| author | Maedeh Khodamoradi Saeed Rafizadeh Tafti Seyed Ali Mousavi Shaegh Behrouz Aflatoonian Mostafa Azimzadeh Patricia Khashayar |
| author_facet | Maedeh Khodamoradi Saeed Rafizadeh Tafti Seyed Ali Mousavi Shaegh Behrouz Aflatoonian Mostafa Azimzadeh Patricia Khashayar |
| author_sort | Maedeh Khodamoradi |
| collection | DOAJ |
| description | Sperm selection is a clinical need for guided fertilization in men with low-quality semen. In this regard, microfluidics can provide an enabling platform for the precise manipulation and separation of high-quality sperm cells through applying various stimuli, including chemical agents, mechanical forces, and thermal gradients. In addition, microfluidic platforms can help to guide sperms and oocytes for controlled in vitro fertilization or sperm sorting using both passive and active methods. Herein, we present a detailed review of the use of various microfluidic methods for sorting and categorizing sperms for different applications. The advantages and disadvantages of each method are further discussed and future perspectives in the field are given. |
| first_indexed | 2024-03-10T10:48:30Z |
| format | Article |
| id | doaj.art-1cdc229aa5ab4e30ac67f5fa56761713 |
| institution | Directory Open Access Journal |
| issn | 2227-9040 |
| language | English |
| last_indexed | 2024-03-10T10:48:30Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Chemosensors |
| spelling | doaj.art-1cdc229aa5ab4e30ac67f5fa567617132023-11-21T22:23:34ZengMDPI AGChemosensors2227-90402021-06-019612610.3390/chemosensors9060126Recent Microfluidic Innovations for Sperm SortingMaedeh Khodamoradi0Saeed Rafizadeh Tafti1Seyed Ali Mousavi Shaegh2Behrouz Aflatoonian3Mostafa Azimzadeh4Patricia Khashayar5Medical Nanotechnology & Tissue Engineering Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd 89195999, IranMedical Nanotechnology & Tissue Engineering Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd 89195999, IranLaboratory for Microfluidics and Medical Microsystems, Bu Ali Research Institute, Mashhad University of Medical Sciences, Mashhad 9196773117, IranMedical Nanotechnology & Tissue Engineering Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd 89195999, IranMedical Nanotechnology & Tissue Engineering Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd 89195999, IranCenter for Microsystems Technology, Imec and Ghent University, 9050 Ghent, BelgiumSperm selection is a clinical need for guided fertilization in men with low-quality semen. In this regard, microfluidics can provide an enabling platform for the precise manipulation and separation of high-quality sperm cells through applying various stimuli, including chemical agents, mechanical forces, and thermal gradients. In addition, microfluidic platforms can help to guide sperms and oocytes for controlled in vitro fertilization or sperm sorting using both passive and active methods. Herein, we present a detailed review of the use of various microfluidic methods for sorting and categorizing sperms for different applications. The advantages and disadvantages of each method are further discussed and future perspectives in the field are given.https://www.mdpi.com/2227-9040/9/6/126microfluidicslab-on-a-chipsperm sortingfertility |
| spellingShingle | Maedeh Khodamoradi Saeed Rafizadeh Tafti Seyed Ali Mousavi Shaegh Behrouz Aflatoonian Mostafa Azimzadeh Patricia Khashayar Recent Microfluidic Innovations for Sperm Sorting Chemosensors microfluidics lab-on-a-chip sperm sorting fertility |
| title | Recent Microfluidic Innovations for Sperm Sorting |
| title_full | Recent Microfluidic Innovations for Sperm Sorting |
| title_fullStr | Recent Microfluidic Innovations for Sperm Sorting |
| title_full_unstemmed | Recent Microfluidic Innovations for Sperm Sorting |
| title_short | Recent Microfluidic Innovations for Sperm Sorting |
| title_sort | recent microfluidic innovations for sperm sorting |
| topic | microfluidics lab-on-a-chip sperm sorting fertility |
| url | https://www.mdpi.com/2227-9040/9/6/126 |
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