Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment
Introduction. As a result of increased production and spread in the environment, nanoparticles can pose a significant risk to public health. To date, the toxicity data of nanoparticles collected, using traditional models and methods, are contradictory and inconsistent. Highlighting the significant m...
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| Format: | Article |
| Language: | English |
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Asociatia de Biosiguranta si Biosecuritate
2020-03-01
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| Series: | One Health & Risk Management |
| Subjects: | |
| Online Access: | https://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/35/21 |
| _version_ | 1811329012835811328 |
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| author | Liliana CEPOI Ludmila RUDI Tatiana CHIRIAC Vera MISCU Valeriu RUDIC |
| author_facet | Liliana CEPOI Ludmila RUDI Tatiana CHIRIAC Vera MISCU Valeriu RUDIC |
| author_sort | Liliana CEPOI |
| collection | DOAJ |
| description | Introduction. As a result of increased production and spread in the environment, nanoparticles can pose a significant risk to public health. To date, the toxicity data of nanoparticles collected, using traditional models and methods, are contradictory and inconsistent. Highlighting the significant methods and markers of nanoparticle toxicity is a current research direction.
Material and methods. The strain of red microalgae Porphyridium cruentum CNM-AR-01, known as a lipid manufacturer, was used as object of study. The toxic effect of CdSe (3-7 nm), ZnSe (40 nm), and ZnS (30-35 nm) nanoparticles was tested. The amount of malondialdehyde was determined based on thiobarbituric acid reactive substances.
Results. A close correlation between the amount of biomass and malondialdehyde in the cells of red microalgae Porphyridium cruentum has been established for nanoparticle concentration ranges which have a toxic effect on Porphyridium cruentum.
Conclusions. Malondialdehyde can be considered as a marker of nanoparticle toxicity. |
| first_indexed | 2024-04-13T15:36:16Z |
| format | Article |
| id | doaj.art-1ce3648b4d15460dbbca0e92c7c78b1c |
| institution | Directory Open Access Journal |
| issn | 2887-3458 2587-3466 |
| language | English |
| last_indexed | 2024-04-13T15:36:16Z |
| publishDate | 2020-03-01 |
| publisher | Asociatia de Biosiguranta si Biosecuritate |
| record_format | Article |
| series | One Health & Risk Management |
| spelling | doaj.art-1ce3648b4d15460dbbca0e92c7c78b1c2022-12-22T02:41:15ZengAsociatia de Biosiguranta si BiosecuritateOne Health & Risk Management2887-34582587-34662020-03-01116471Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environmentLiliana CEPOI0https://orcid.org/0000-0002-7516-948XLudmila RUDI1https://orcid.org/0000-0002-0752-8153Tatiana CHIRIAC2https://orcid.org/0000-0003-2933-0751Vera MISCU3Valeriu RUDIC4https://orcid.org/0000-0001-8090-3004Institutul de Microbiologie și BiotehnologieInstitutul de Microbiologie și BiotehnologieInstitutul de Microbiologie și BiotehnologieInstitutul de Microbiologie și BiotehnologieInstitutul de Microbiologie și BiotehnologieIntroduction. As a result of increased production and spread in the environment, nanoparticles can pose a significant risk to public health. To date, the toxicity data of nanoparticles collected, using traditional models and methods, are contradictory and inconsistent. Highlighting the significant methods and markers of nanoparticle toxicity is a current research direction. Material and methods. The strain of red microalgae Porphyridium cruentum CNM-AR-01, known as a lipid manufacturer, was used as object of study. The toxic effect of CdSe (3-7 nm), ZnSe (40 nm), and ZnS (30-35 nm) nanoparticles was tested. The amount of malondialdehyde was determined based on thiobarbituric acid reactive substances. Results. A close correlation between the amount of biomass and malondialdehyde in the cells of red microalgae Porphyridium cruentum has been established for nanoparticle concentration ranges which have a toxic effect on Porphyridium cruentum. Conclusions. Malondialdehyde can be considered as a marker of nanoparticle toxicity.https://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/35/21nanoparticlestoxicity testsmalondialdehydeporphyridium cruentum |
| spellingShingle | Liliana CEPOI Ludmila RUDI Tatiana CHIRIAC Vera MISCU Valeriu RUDIC Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment One Health & Risk Management nanoparticles toxicity tests malondialdehyde porphyridium cruentum |
| title | Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment |
| title_full | Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment |
| title_fullStr | Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment |
| title_full_unstemmed | Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment |
| title_short | Malondialdehyde - a potential marker of nanoparticle toxicity in an aquatic environment |
| title_sort | malondialdehyde a potential marker of nanoparticle toxicity in an aquatic environment |
| topic | nanoparticles toxicity tests malondialdehyde porphyridium cruentum |
| url | https://journal.ohrm.bba.md/index.php/journal-ohrm-bba-md/article/view/35/21 |
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