Impact of Brain Injury on Processing of Emotional Prosodies in Neonates
Being able to appropriately process different emotional prosodies is an important cognitive ability normally present at birth. In this study, we used event-related potential (ERP) to assess whether brain injury impacts the ability to process different emotional prosodies (happy, fear, and neutral) i...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-05-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fped.2019.00192/full |
| _version_ | 1819029335055532032 |
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| author | Guoyu Sun Hui Xie Yanan Liu Yu Chen Xinlin Hou Dandan Zhang Dandan Zhang |
| author_facet | Guoyu Sun Hui Xie Yanan Liu Yu Chen Xinlin Hou Dandan Zhang Dandan Zhang |
| author_sort | Guoyu Sun |
| collection | DOAJ |
| description | Being able to appropriately process different emotional prosodies is an important cognitive ability normally present at birth. In this study, we used event-related potential (ERP) to assess whether brain injury impacts the ability to process different emotional prosodies (happy, fear, and neutral) in neonates; whether the ERP measure has potential value for the evaluation of neurodevelopmental outcome in later childhood. A total of 42 full-term neonates were recruited from the neonatology department of Peking University First Hospital from June 2014 to January 2015. They were assigned to the brain injury group (n = 20) or control group (n = 22) according to their clinical manifestations, physical examinations, cranial images and routine EEG outcomes. Using an oddball paradigm, ERP data were recorded while subjects listened to happy (20%, deviation stimulus), fearful (20%, deviation stimulus) and neutral (80%, standard stimulus) prosodies to evaluate the potential prognostic value of ERP indexes for neurodevelopment at 30 months of age. Results showed that while the mismatch responses (MMRs) at the frontal lobe were larger for fearful than happy prosody in control neonates, this difference was not observed in neonates with brain injuries. This finding suggests that perinatal brain injury may influence the cognitive ability to process different emotional prosodies in neonatal brain; this deficit could be reflected by decreased MMR amplitudes in response to fearful prosody. Moreover, the decreased MMRs at the frontal lobe was associated with impaired neurodevelopment at 30 months old. |
| first_indexed | 2024-12-21T06:12:37Z |
| format | Article |
| id | doaj.art-1ce4598c03904ea894e6299ba26b331a |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-12-21T06:12:37Z |
| publishDate | 2019-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-1ce4598c03904ea894e6299ba26b331a2022-12-21T19:13:29ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602019-05-01710.3389/fped.2019.00192450708Impact of Brain Injury on Processing of Emotional Prosodies in NeonatesGuoyu Sun0Hui Xie1Yanan Liu2Yu Chen3Xinlin Hou4Dandan Zhang5Dandan Zhang6Department of Pediatrics, Peking University First Hospital, Beijing, ChinaCollege of Psychology, Shenzhen University, Shenzhen, ChinaDepartment of Pediatrics, Peking University First Hospital, Beijing, ChinaCollege of Psychology, Shenzhen University, Shenzhen, ChinaDepartment of Pediatrics, Peking University First Hospital, Beijing, ChinaCollege of Psychology, Shenzhen University, Shenzhen, ChinaShenzhen Key Laboratory of Affective and Social Cognitive Science, Shenzhen University, Shenzhen, ChinaBeing able to appropriately process different emotional prosodies is an important cognitive ability normally present at birth. In this study, we used event-related potential (ERP) to assess whether brain injury impacts the ability to process different emotional prosodies (happy, fear, and neutral) in neonates; whether the ERP measure has potential value for the evaluation of neurodevelopmental outcome in later childhood. A total of 42 full-term neonates were recruited from the neonatology department of Peking University First Hospital from June 2014 to January 2015. They were assigned to the brain injury group (n = 20) or control group (n = 22) according to their clinical manifestations, physical examinations, cranial images and routine EEG outcomes. Using an oddball paradigm, ERP data were recorded while subjects listened to happy (20%, deviation stimulus), fearful (20%, deviation stimulus) and neutral (80%, standard stimulus) prosodies to evaluate the potential prognostic value of ERP indexes for neurodevelopment at 30 months of age. Results showed that while the mismatch responses (MMRs) at the frontal lobe were larger for fearful than happy prosody in control neonates, this difference was not observed in neonates with brain injuries. This finding suggests that perinatal brain injury may influence the cognitive ability to process different emotional prosodies in neonatal brain; this deficit could be reflected by decreased MMR amplitudes in response to fearful prosody. Moreover, the decreased MMRs at the frontal lobe was associated with impaired neurodevelopment at 30 months old.https://www.frontiersin.org/article/10.3389/fped.2019.00192/fullneonatebrain injuryemotional prosodyevent-related potentialfearhappy |
| spellingShingle | Guoyu Sun Hui Xie Yanan Liu Yu Chen Xinlin Hou Dandan Zhang Dandan Zhang Impact of Brain Injury on Processing of Emotional Prosodies in Neonates Frontiers in Pediatrics neonate brain injury emotional prosody event-related potential fear happy |
| title | Impact of Brain Injury on Processing of Emotional Prosodies in Neonates |
| title_full | Impact of Brain Injury on Processing of Emotional Prosodies in Neonates |
| title_fullStr | Impact of Brain Injury on Processing of Emotional Prosodies in Neonates |
| title_full_unstemmed | Impact of Brain Injury on Processing of Emotional Prosodies in Neonates |
| title_short | Impact of Brain Injury on Processing of Emotional Prosodies in Neonates |
| title_sort | impact of brain injury on processing of emotional prosodies in neonates |
| topic | neonate brain injury emotional prosody event-related potential fear happy |
| url | https://www.frontiersin.org/article/10.3389/fped.2019.00192/full |
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