Malaria parasite LIMP protein regulates sporozoite gliding motility and infectivity in mosquito and mammalian hosts

Malaria parasite LIMP protein regulates sporozoite gliding motility and infectivity in mosquito and mammalian hosts

Gliding motility allows malaria parasites to migrate and invade tissues and cells in different hosts. It requires parasite surface proteins to provide attachment to host cells and extracellular matrices. Here, we identify the Plasmodium protein LIMP (the name refers to a gliding phenotype in the spo...

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Bibliographic Details
Main Authors: Jorge M Santos, Saskia Egarter, Vanessa Zuzarte-Luís, Hirdesh Kumar, Catherine A Moreau, Jessica Kehrer, Andreia Pinto, Mário da Costa, Blandine Franke-Fayard, Chris J Janse, Friedrich Frischknecht, Gunnar R Mair
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-05-01
Series:eLife
Subjects:
malaria
transmission
gliding motility
Plasmodium berghei
cell adhesion
Online Access:https://elifesciences.org/articles/24109

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