Inhibitory Control and the Structural Parcelation of the Right Inferior Frontal Gyrus
The right inferior frontal gyrus (rIFG) has most strongly, although not exclusively, been associated with response inhibition, not least based on covariations of behavioral performance measures and local gray matter characteristics. However, the white matter microstructure of the rIFG as well as its...
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| Format: | Article |
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Frontiers Media S.A.
2022-02-01
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| Series: | Frontiers in Human Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnhum.2022.787079/full |
| _version_ | 1818330970455015424 |
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| author | Rune Boen Rune Boen Rune Boen Liisa Raud Liisa Raud Rene J. Huster Rene J. Huster Rene J. Huster |
| author_facet | Rune Boen Rune Boen Rune Boen Liisa Raud Liisa Raud Rene J. Huster Rene J. Huster Rene J. Huster |
| author_sort | Rune Boen |
| collection | DOAJ |
| description | The right inferior frontal gyrus (rIFG) has most strongly, although not exclusively, been associated with response inhibition, not least based on covariations of behavioral performance measures and local gray matter characteristics. However, the white matter microstructure of the rIFG as well as its connectivity has been less in focus, especially when it comes to the consideration of potential subdivisions within this area. The present study reconstructed the structural connections of the three main subregions of the rIFG (i.e., pars opercularis, pars triangularis, and pars orbitalis) using diffusion tensor imaging, and further assessed their associations with behavioral measures of inhibitory control. The results revealed a marked heterogeneity of the three subregions with respect to the pattern and extent of their connections, with the pars orbitalis showing the most widespread inter-regional connectivity, while the pars opercularis showed the lowest number of interconnected regions. When relating behavioral performance measures of a stop signal task to brain structure, the data indicated an association between the dorsal opercular connectivity and the go reaction time and the stopping accuracy. |
| first_indexed | 2024-12-13T13:12:25Z |
| format | Article |
| id | doaj.art-1ce631708ed542a698213c98b1bfd45e |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-13T13:12:25Z |
| publishDate | 2022-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-1ce631708ed542a698213c98b1bfd45e2022-12-21T23:44:39ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612022-02-011610.3389/fnhum.2022.787079787079Inhibitory Control and the Structural Parcelation of the Right Inferior Frontal GyrusRune Boen0Rune Boen1Rune Boen2Liisa Raud3Liisa Raud4Rene J. Huster5Rene J. Huster6Rene J. Huster7Multimodal Imaging and Cognitive Control Lab, Department of Psychology, University of Oslo, Oslo, NorwayDepartment of Medical Genetics, Oslo University Hospital, Oslo, NorwayNORMENT, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, NorwayCognitive and Translational Neuroscience Cluster, Department of Psychology, University of Oslo, Oslo, NorwayCenter for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo, NorwayMultimodal Imaging and Cognitive Control Lab, Department of Psychology, University of Oslo, Oslo, NorwayCognitive and Translational Neuroscience Cluster, Department of Psychology, University of Oslo, Oslo, NorwaySleep Unit, Department of Otorhinolaryngology/Head and Neck Surgery, Lovisenberg Diakonale Hospital, Oslo, NorwayThe right inferior frontal gyrus (rIFG) has most strongly, although not exclusively, been associated with response inhibition, not least based on covariations of behavioral performance measures and local gray matter characteristics. However, the white matter microstructure of the rIFG as well as its connectivity has been less in focus, especially when it comes to the consideration of potential subdivisions within this area. The present study reconstructed the structural connections of the three main subregions of the rIFG (i.e., pars opercularis, pars triangularis, and pars orbitalis) using diffusion tensor imaging, and further assessed their associations with behavioral measures of inhibitory control. The results revealed a marked heterogeneity of the three subregions with respect to the pattern and extent of their connections, with the pars orbitalis showing the most widespread inter-regional connectivity, while the pars opercularis showed the lowest number of interconnected regions. When relating behavioral performance measures of a stop signal task to brain structure, the data indicated an association between the dorsal opercular connectivity and the go reaction time and the stopping accuracy.https://www.frontiersin.org/articles/10.3389/fnhum.2022.787079/fullstructural parcelationright inferior frontal gyrusinhibitory controlresponse executionresponse inhibition |
| spellingShingle | Rune Boen Rune Boen Rune Boen Liisa Raud Liisa Raud Rene J. Huster Rene J. Huster Rene J. Huster Inhibitory Control and the Structural Parcelation of the Right Inferior Frontal Gyrus Frontiers in Human Neuroscience structural parcelation right inferior frontal gyrus inhibitory control response execution response inhibition |
| title | Inhibitory Control and the Structural Parcelation of the Right Inferior Frontal Gyrus |
| title_full | Inhibitory Control and the Structural Parcelation of the Right Inferior Frontal Gyrus |
| title_fullStr | Inhibitory Control and the Structural Parcelation of the Right Inferior Frontal Gyrus |
| title_full_unstemmed | Inhibitory Control and the Structural Parcelation of the Right Inferior Frontal Gyrus |
| title_short | Inhibitory Control and the Structural Parcelation of the Right Inferior Frontal Gyrus |
| title_sort | inhibitory control and the structural parcelation of the right inferior frontal gyrus |
| topic | structural parcelation right inferior frontal gyrus inhibitory control response execution response inhibition |
| url | https://www.frontiersin.org/articles/10.3389/fnhum.2022.787079/full |
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