Full-Length Recombinant hSP-D Binds and Inhibits SARS-CoV-2

Full-Length Recombinant hSP-D Binds and Inhibits SARS-CoV-2

SARS-CoV-2 infection of host cells is driven by binding of the SARS-CoV-2 spike-(S)-protein to lung type II pneumocytes, followed by virus replication. Surfactant protein SP-D, member of the front-line immune defense of the lungs, binds glycosylated structures on invading pathogens such as viruses t...

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Bibliografiske detaljer
Main Authors: Raquel Arroyo, Shawn N. Grant, Miriam Colombo, Lucia Salvioni, Fabio Corsi, Marta Truffi, Davide Ottolina, Brett Hurst, Marc Salzberg, Davide Prosperi, Paul S. Kingma
Format: Article
Sprog:English
Udgivet: MDPI AG 2021-07-01
Serier:Biomolecules
Fag:
SP-D
COVID-19
spike-protein
ACE2
anti-inflammatory
Online adgang:https://www.mdpi.com/2218-273X/11/8/1114

Internet

https://www.mdpi.com/2218-273X/11/8/1114

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