Obesity, Impaired Glucose Metabolism and Hepatic Histopathological Damage in 3xTg-AD Mice at Different Stages of Disease Compared to Mice with Normal Aging

Obesity, Impaired Glucose Metabolism and Hepatic Histopathological Damage in 3xTg-AD Mice at Different Stages of Disease Compared to Mice with Normal Aging

The crosstalk between obesity, diabetes, steatohepatitis, and dementia creates a controversial scenario when also studied using animal models. In the present work, this crosstalk was investigated in male and female 3xTg-AD mice for Alzheimer’s disease (AD) at different ages/stages and compared to se...

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Bibliographic Details
Main Authors: Clara Pérez-Gozalbo, Lydia Giménez-Llort
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biology and Life Sciences Forum
Subjects:
obesity
glucose metabolism
liver
dementia
Alzheimer’s disease
aging
Online Access:https://www.mdpi.com/2673-9976/19/1/10

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