Comparison of long-term radial artery occlusion via distal vs. conventional transradial access (CONDITION): a randomized controlled trial
Abstract Background The distal transradial access (dTRA) has become an attractive and alternative access to the conventional transradial access (TRA) for cardiovascular interventional diagnosis and/or treatment. There was a lack of randomized clinical trials to evaluate the effect of the dTRA on the...
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| Format: | Article |
| Language: | English |
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BMC
2024-02-01
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| Series: | BMC Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12916-024-03281-7 |
| _version_ | 1827327168426803200 |
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| author | Tao Chen Lamei Li Feng Li Wei Lu Ganwei Shi Wenhua Li Anni Yang Hui Huang Jianqiang Xiao Qiuwei Zhang Jun Gu Sheliang Xue Liuyan Zhang Li Li Lingxia Xu Rongrong Ji Haibo Wang Gaojun Cai |
| author_facet | Tao Chen Lamei Li Feng Li Wei Lu Ganwei Shi Wenhua Li Anni Yang Hui Huang Jianqiang Xiao Qiuwei Zhang Jun Gu Sheliang Xue Liuyan Zhang Li Li Lingxia Xu Rongrong Ji Haibo Wang Gaojun Cai |
| author_sort | Tao Chen |
| collection | DOAJ |
| description | Abstract Background The distal transradial access (dTRA) has become an attractive and alternative access to the conventional transradial access (TRA) for cardiovascular interventional diagnosis and/or treatment. There was a lack of randomized clinical trials to evaluate the effect of the dTRA on the long-term radial artery occlusion (RAO). Methods This was a prospective, randomized controlled study. The primary endpoint was the incidence of long-term RAO at 3 months after discharge. The secondary endpoints included the successful puncture rate, puncture time, and other access-related complications. Results The incidence of long-term RAO was 0.8% (3/361) for dTRA and 3.3% (12/365) for TRA (risk ratio = 0.25, 95% confidence interval = 0.07–0.88, P = 0.02). The incidence of RAO at 24 h was significantly lower in the dTRA group than in the TRA group (2.5% vs. 6.7%, P < 0.01). The puncture success rate (96.0% vs. 98.5%, P = 0.03) and single puncture attempt (70.9% vs. 83.9%, P < 0.01) were significantly lower in the dTRA group than in the TRA group. However, the number of puncture attempts and puncture time were higher in the dTRA group. The dTRA group had a lower incidence of bleeding than the TRA group (1.5% vs. 6.0%, P < 0.01). There was no difference in the success rate of the procedure, total fluoroscopy time, or incidence of other access-related complications between the two groups. In the per-protocol analysis, the incidence of mEASY type ≥ II haematoma was significantly lower in the dTRA group, which was consistent with that in the as-treated analysis. Conclusions The dTRA significantly reduced the incidence of long-term RAO, bleeding or haematoma. Trial registration ClinicalTrials.gov identifer: NCT05253820. |
| first_indexed | 2024-03-07T14:57:12Z |
| format | Article |
| id | doaj.art-1ce940d1628a4a709b3dc516f7ac4b99 |
| institution | Directory Open Access Journal |
| issn | 1741-7015 |
| language | English |
| last_indexed | 2024-03-07T14:57:12Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medicine |
| spelling | doaj.art-1ce940d1628a4a709b3dc516f7ac4b992024-03-05T19:21:48ZengBMCBMC Medicine1741-70152024-02-0122111310.1186/s12916-024-03281-7Comparison of long-term radial artery occlusion via distal vs. conventional transradial access (CONDITION): a randomized controlled trialTao Chen0Lamei Li1Feng Li2Wei Lu3Ganwei Shi4Wenhua Li5Anni Yang6Hui Huang7Jianqiang Xiao8Qiuwei Zhang9Jun Gu10Sheliang Xue11Liuyan Zhang12Li Li13Lingxia Xu14Rongrong Ji15Haibo Wang16Gaojun Cai17Department of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Jiangyin Hospital of Traditional Chinese MedicineDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Catheter Room, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityPeking University Clinical Research Institute, Peking University First HospitalDepartment of Cardiology, Wujin Hospital Affiliated With Jiangsu University, The Wujin Clinical College of Xuzhou Medical UniversityAbstract Background The distal transradial access (dTRA) has become an attractive and alternative access to the conventional transradial access (TRA) for cardiovascular interventional diagnosis and/or treatment. There was a lack of randomized clinical trials to evaluate the effect of the dTRA on the long-term radial artery occlusion (RAO). Methods This was a prospective, randomized controlled study. The primary endpoint was the incidence of long-term RAO at 3 months after discharge. The secondary endpoints included the successful puncture rate, puncture time, and other access-related complications. Results The incidence of long-term RAO was 0.8% (3/361) for dTRA and 3.3% (12/365) for TRA (risk ratio = 0.25, 95% confidence interval = 0.07–0.88, P = 0.02). The incidence of RAO at 24 h was significantly lower in the dTRA group than in the TRA group (2.5% vs. 6.7%, P < 0.01). The puncture success rate (96.0% vs. 98.5%, P = 0.03) and single puncture attempt (70.9% vs. 83.9%, P < 0.01) were significantly lower in the dTRA group than in the TRA group. However, the number of puncture attempts and puncture time were higher in the dTRA group. The dTRA group had a lower incidence of bleeding than the TRA group (1.5% vs. 6.0%, P < 0.01). There was no difference in the success rate of the procedure, total fluoroscopy time, or incidence of other access-related complications between the two groups. In the per-protocol analysis, the incidence of mEASY type ≥ II haematoma was significantly lower in the dTRA group, which was consistent with that in the as-treated analysis. Conclusions The dTRA significantly reduced the incidence of long-term RAO, bleeding or haematoma. Trial registration ClinicalTrials.gov identifer: NCT05253820.https://doi.org/10.1186/s12916-024-03281-7Distal transradial accessTransradial accessRadial artery occlusionRandomized controlled trial |
| spellingShingle | Tao Chen Lamei Li Feng Li Wei Lu Ganwei Shi Wenhua Li Anni Yang Hui Huang Jianqiang Xiao Qiuwei Zhang Jun Gu Sheliang Xue Liuyan Zhang Li Li Lingxia Xu Rongrong Ji Haibo Wang Gaojun Cai Comparison of long-term radial artery occlusion via distal vs. conventional transradial access (CONDITION): a randomized controlled trial BMC Medicine Distal transradial access Transradial access Radial artery occlusion Randomized controlled trial |
| title | Comparison of long-term radial artery occlusion via distal vs. conventional transradial access (CONDITION): a randomized controlled trial |
| title_full | Comparison of long-term radial artery occlusion via distal vs. conventional transradial access (CONDITION): a randomized controlled trial |
| title_fullStr | Comparison of long-term radial artery occlusion via distal vs. conventional transradial access (CONDITION): a randomized controlled trial |
| title_full_unstemmed | Comparison of long-term radial artery occlusion via distal vs. conventional transradial access (CONDITION): a randomized controlled trial |
| title_short | Comparison of long-term radial artery occlusion via distal vs. conventional transradial access (CONDITION): a randomized controlled trial |
| title_sort | comparison of long term radial artery occlusion via distal vs conventional transradial access condition a randomized controlled trial |
| topic | Distal transradial access Transradial access Radial artery occlusion Randomized controlled trial |
| url | https://doi.org/10.1186/s12916-024-03281-7 |
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