Effects of COVID-19 Pandemic Confinement in Patients With Cognitive Impairment
Introduction: State of emergency caused by COVID-19 pandemic and subsequent lockdown hit Spain on 14th March 2020 and lasted until 21st June 2020. Social isolation measures were applied. Medical attention was focused on COVID-19. Primary and social care were mainly performed by telephone. This excep...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-11-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2020.589901/full |
| _version_ | 1828542866809421824 |
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| author | Ainara Barguilla Aida Fernández-Lebrero Aida Fernández-Lebrero Aida Fernández-Lebrero Isabel Estragués-Gázquez Greta García-Escobar Irene Navalpotro-Gómez Irene Navalpotro-Gómez Irene Navalpotro-Gómez Rosa María Manero Rosa María Manero Víctor Puente-Periz Víctor Puente-Periz Víctor Puente-Periz Jaume Roquer Albert Puig-Pijoan Albert Puig-Pijoan Albert Puig-Pijoan |
| author_facet | Ainara Barguilla Aida Fernández-Lebrero Aida Fernández-Lebrero Aida Fernández-Lebrero Isabel Estragués-Gázquez Greta García-Escobar Irene Navalpotro-Gómez Irene Navalpotro-Gómez Irene Navalpotro-Gómez Rosa María Manero Rosa María Manero Víctor Puente-Periz Víctor Puente-Periz Víctor Puente-Periz Jaume Roquer Albert Puig-Pijoan Albert Puig-Pijoan Albert Puig-Pijoan |
| author_sort | Ainara Barguilla |
| collection | DOAJ |
| description | Introduction: State of emergency caused by COVID-19 pandemic and subsequent lockdown hit Spain on 14th March 2020 and lasted until 21st June 2020. Social isolation measures were applied. Medical attention was focused on COVID-19. Primary and social care were mainly performed by telephone. This exceptional situation may affect especially vulnerable patients such as people living with dementia. Our aim was to describe the influence of restrictive measures on patients living with mild cognitive decline and dementia evaluating SARS-CoV2 infection, changes in routines, cognitive decline stage, neuropsychiatric symptoms, delirium, falls, caregiver stress, and access to sanitary care.Materials and Methods: We gathered MCI and dementia patients with clinical follow-up before and after confinement from DegMar registry (Hospital del Mar). A telephone ad-hoc questionnaire was administered. Global status was assessed using CDR scale. Changes in neuropsychiatric symptoms were assessed by Neuropsychiatric Inventory (NPI) and retrospective interview for pre-confinement base characteristics.Results: We contacted a total of 60 patients, age 75.4 years ± 5,192. 53.3% were women. Alzheimer's Disease (41.7%) and Mild Cognitive Impairment (25%) were the most prevalent diagnosis. Remaining cases included different dementia disorders. A total of 10% of patients had been diagnosed with SARS-CoV-2. During confinement 70% of patients abandoned previous daily activities, 60% had cognitive worsening reported by relatives/caretakers, 15% presented delirium episodes, and 13% suffered increased incidence of falls. Caregivers reported an increased burden in 41% cases and burnout in 11% cases. 16% reported difficulties accessing medical care, 33% received medical phone assistance, 20% needed emergency care and 21% had changes in psychopharmacological therapies. Neuropsychiatric profile globally worsened (p < 0.000), also in particular items like agitation (p = 0.003), depression (p < 0.000), anxiety (p < 0.000) and changes in appetite (p = 0.004).Conclusion: SARS-CoV2-related lockdown resulted in an important effect over social and cognitive spheres and worsening of neuropsychiatric traits in patients living with mild cognitive decline and dementia. Although the uncertainty regarding the evolution of the pandemic makes strategy difficult, we need to reach patients and caregivers and develop adequate strategies to reinforce and adapt social and health care. |
| first_indexed | 2024-12-12T02:03:41Z |
| format | Article |
| id | doaj.art-1ceac9167f8b44d9bda83946d6ea3bc0 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-12T02:03:41Z |
| publishDate | 2020-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-1ceac9167f8b44d9bda83946d6ea3bc02022-12-22T00:42:06ZengFrontiers Media S.A.Frontiers in Neurology1664-22952020-11-011110.3389/fneur.2020.589901589901Effects of COVID-19 Pandemic Confinement in Patients With Cognitive ImpairmentAinara Barguilla0Aida Fernández-Lebrero1Aida Fernández-Lebrero2Aida Fernández-Lebrero3Isabel Estragués-Gázquez4Greta García-Escobar5Irene Navalpotro-Gómez6Irene Navalpotro-Gómez7Irene Navalpotro-Gómez8Rosa María Manero9Rosa María Manero10Víctor Puente-Periz11Víctor Puente-Periz12Víctor Puente-Periz13Jaume Roquer14Albert Puig-Pijoan15Albert Puig-Pijoan16Albert Puig-Pijoan17Neurology Department, Hospital del Mar, Barcelona, SpainNeurology Department, Hospital del Mar, Barcelona, SpainCognitive Impairment and Movement Disorders Unit, Neurology Department, Hospital del Mar, Barcelona, SpainNeurofunctionality and Language Group, Neurosciences Program, Hospital del Mar Research Institute (IMIM), Barcelona, SpainNeurology Department, Hospital del Mar, Barcelona, SpainNeurofunctionality and Language Group, Neurosciences Program, Hospital del Mar Research Institute (IMIM), Barcelona, SpainNeurology Department, Hospital del Mar, Barcelona, SpainCognitive Impairment and Movement Disorders Unit, Neurology Department, Hospital del Mar, Barcelona, SpainNeurofunctionality and Language Group, Neurosciences Program, Hospital del Mar Research Institute (IMIM), Barcelona, SpainCognitive Impairment and Movement Disorders Unit, Neurology Department, Hospital del Mar, Barcelona, SpainNeurofunctionality and Language Group, Neurosciences Program, Hospital del Mar Research Institute (IMIM), Barcelona, SpainNeurology Department, Hospital del Mar, Barcelona, SpainCognitive Impairment and Movement Disorders Unit, Neurology Department, Hospital del Mar, Barcelona, SpainNeurofunctionality and Language Group, Neurosciences Program, Hospital del Mar Research Institute (IMIM), Barcelona, SpainNeurology Department, Hospital del Mar, Barcelona, SpainNeurology Department, Hospital del Mar, Barcelona, SpainCognitive Impairment and Movement Disorders Unit, Neurology Department, Hospital del Mar, Barcelona, SpainNeurofunctionality and Language Group, Neurosciences Program, Hospital del Mar Research Institute (IMIM), Barcelona, SpainIntroduction: State of emergency caused by COVID-19 pandemic and subsequent lockdown hit Spain on 14th March 2020 and lasted until 21st June 2020. Social isolation measures were applied. Medical attention was focused on COVID-19. Primary and social care were mainly performed by telephone. This exceptional situation may affect especially vulnerable patients such as people living with dementia. Our aim was to describe the influence of restrictive measures on patients living with mild cognitive decline and dementia evaluating SARS-CoV2 infection, changes in routines, cognitive decline stage, neuropsychiatric symptoms, delirium, falls, caregiver stress, and access to sanitary care.Materials and Methods: We gathered MCI and dementia patients with clinical follow-up before and after confinement from DegMar registry (Hospital del Mar). A telephone ad-hoc questionnaire was administered. Global status was assessed using CDR scale. Changes in neuropsychiatric symptoms were assessed by Neuropsychiatric Inventory (NPI) and retrospective interview for pre-confinement base characteristics.Results: We contacted a total of 60 patients, age 75.4 years ± 5,192. 53.3% were women. Alzheimer's Disease (41.7%) and Mild Cognitive Impairment (25%) were the most prevalent diagnosis. Remaining cases included different dementia disorders. A total of 10% of patients had been diagnosed with SARS-CoV-2. During confinement 70% of patients abandoned previous daily activities, 60% had cognitive worsening reported by relatives/caretakers, 15% presented delirium episodes, and 13% suffered increased incidence of falls. Caregivers reported an increased burden in 41% cases and burnout in 11% cases. 16% reported difficulties accessing medical care, 33% received medical phone assistance, 20% needed emergency care and 21% had changes in psychopharmacological therapies. Neuropsychiatric profile globally worsened (p < 0.000), also in particular items like agitation (p = 0.003), depression (p < 0.000), anxiety (p < 0.000) and changes in appetite (p = 0.004).Conclusion: SARS-CoV2-related lockdown resulted in an important effect over social and cognitive spheres and worsening of neuropsychiatric traits in patients living with mild cognitive decline and dementia. Although the uncertainty regarding the evolution of the pandemic makes strategy difficult, we need to reach patients and caregivers and develop adequate strategies to reinforce and adapt social and health care.https://www.frontiersin.org/articles/10.3389/fneur.2020.589901/fullCOVID- 19SARS - CoV-2dementiadepressioncognitive impairmentanxiety |
| spellingShingle | Ainara Barguilla Aida Fernández-Lebrero Aida Fernández-Lebrero Aida Fernández-Lebrero Isabel Estragués-Gázquez Greta García-Escobar Irene Navalpotro-Gómez Irene Navalpotro-Gómez Irene Navalpotro-Gómez Rosa María Manero Rosa María Manero Víctor Puente-Periz Víctor Puente-Periz Víctor Puente-Periz Jaume Roquer Albert Puig-Pijoan Albert Puig-Pijoan Albert Puig-Pijoan Effects of COVID-19 Pandemic Confinement in Patients With Cognitive Impairment Frontiers in Neurology COVID- 19 SARS - CoV-2 dementia depression cognitive impairment anxiety |
| title | Effects of COVID-19 Pandemic Confinement in Patients With Cognitive Impairment |
| title_full | Effects of COVID-19 Pandemic Confinement in Patients With Cognitive Impairment |
| title_fullStr | Effects of COVID-19 Pandemic Confinement in Patients With Cognitive Impairment |
| title_full_unstemmed | Effects of COVID-19 Pandemic Confinement in Patients With Cognitive Impairment |
| title_short | Effects of COVID-19 Pandemic Confinement in Patients With Cognitive Impairment |
| title_sort | effects of covid 19 pandemic confinement in patients with cognitive impairment |
| topic | COVID- 19 SARS - CoV-2 dementia depression cognitive impairment anxiety |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2020.589901/full |
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