Nutritional Management of Thyroiditis of Hashimoto

Since the thyroid gland is one of the organs most affected by autoimmune processes, many patients with thyroiditis of Hashimoto (TH) seek medical advice on lifestyle variance and dietary modifications to improve and maintain their hyroid function. In this review, we aim to present and discuss some c...

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Main Authors: Yana Danailova, Tsvetelina Velikova, Georgi Nikolaev, Zorka Mitova, Alexander Shinkov, Hristo Gagov, Rossitza Konakchieva
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/9/5144
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author Yana Danailova
Tsvetelina Velikova
Georgi Nikolaev
Zorka Mitova
Alexander Shinkov
Hristo Gagov
Rossitza Konakchieva
author_facet Yana Danailova
Tsvetelina Velikova
Georgi Nikolaev
Zorka Mitova
Alexander Shinkov
Hristo Gagov
Rossitza Konakchieva
author_sort Yana Danailova
collection DOAJ
description Since the thyroid gland is one of the organs most affected by autoimmune processes, many patients with thyroiditis of Hashimoto (TH) seek medical advice on lifestyle variance and dietary modifications to improve and maintain their hyroid function. In this review, we aim to present and discuss some challenges associated with the nutritional management of TH, focusing on environmental and dietary deficits, inflammatory and toxic nutrients, cyanotoxins, etc. We discuss the relationships among different diets, chronic inflammation, and microbiota, and their impact on the development and exacerbation of TH in detail. We share some novel insights into the role of vitamin D and melatonin for preserving thyroid function during chronic inflammation in autoimmune predisposed subjects. A comprehensive overview is provided on anti-inflammatory nutrients and ecological diets, including foods for cleansing and detoxification, which represent strategies to prevent relapses and achieve overall improvement of life quality. In conclusion, data from biomedical and clinical studies provide evidence that an appropriate dietary and lighting regimen could significantly improve the function of the thyroid gland and reduce the reactivity of autoantibodies in TH. Compliance with nutritional guidelines may help TH patients to reduce the need for medicines.
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spelling doaj.art-1cf05ae9245e4c798d1efb93226c50b32023-11-23T08:27:50ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-05-01239514410.3390/ijms23095144Nutritional Management of Thyroiditis of HashimotoYana Danailova0Tsvetelina Velikova1Georgi Nikolaev2Zorka Mitova3Alexander Shinkov4Hristo Gagov5Rossitza Konakchieva6Department of Animal and Human Physiology, Faculty of Biology, Sofia University “St. Kliment Ohridski”, 8 Dragan Tsankov Blvd., 1164 Sofia, BulgariaDepartment of Clinical Immunology, University Hospital Lozenetsz, Sofia University St. Kliement Ohridski, 1 “Kozyak” St., 1407 Sofia, BulgariaDepartment of Cell and Developmental Biology, Faculty of Biology, Sofia University “St. Kliment Ohridski”, 8 Dragan Tsankov Blvd., 1164 Sofia, BulgariaInstitute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Blvd. 25, 1113 Sofia, BulgariaDepartment of Endocrinology, Medical Faculty, Medical University of Sofia, 2 Zdrave St., 1431 Sofia, BulgariaDepartment of Animal and Human Physiology, Faculty of Biology, Sofia University “St. Kliment Ohridski”, 8 Dragan Tsankov Blvd., 1164 Sofia, BulgariaDepartment of Cell and Developmental Biology, Faculty of Biology, Sofia University “St. Kliment Ohridski”, 8 Dragan Tsankov Blvd., 1164 Sofia, BulgariaSince the thyroid gland is one of the organs most affected by autoimmune processes, many patients with thyroiditis of Hashimoto (TH) seek medical advice on lifestyle variance and dietary modifications to improve and maintain their hyroid function. In this review, we aim to present and discuss some challenges associated with the nutritional management of TH, focusing on environmental and dietary deficits, inflammatory and toxic nutrients, cyanotoxins, etc. We discuss the relationships among different diets, chronic inflammation, and microbiota, and their impact on the development and exacerbation of TH in detail. We share some novel insights into the role of vitamin D and melatonin for preserving thyroid function during chronic inflammation in autoimmune predisposed subjects. A comprehensive overview is provided on anti-inflammatory nutrients and ecological diets, including foods for cleansing and detoxification, which represent strategies to prevent relapses and achieve overall improvement of life quality. In conclusion, data from biomedical and clinical studies provide evidence that an appropriate dietary and lighting regimen could significantly improve the function of the thyroid gland and reduce the reactivity of autoantibodies in TH. Compliance with nutritional guidelines may help TH patients to reduce the need for medicines.https://www.mdpi.com/1422-0067/23/9/5144autoimmune Hashimoto’s thyroiditisproinflammatoryanti-inflammatory nutrientsdetoxificationecological diet
spellingShingle Yana Danailova
Tsvetelina Velikova
Georgi Nikolaev
Zorka Mitova
Alexander Shinkov
Hristo Gagov
Rossitza Konakchieva
Nutritional Management of Thyroiditis of Hashimoto
International Journal of Molecular Sciences
autoimmune Hashimoto’s thyroiditis
proinflammatory
anti-inflammatory nutrients
detoxification
ecological diet
title Nutritional Management of Thyroiditis of Hashimoto
title_full Nutritional Management of Thyroiditis of Hashimoto
title_fullStr Nutritional Management of Thyroiditis of Hashimoto
title_full_unstemmed Nutritional Management of Thyroiditis of Hashimoto
title_short Nutritional Management of Thyroiditis of Hashimoto
title_sort nutritional management of thyroiditis of hashimoto
topic autoimmune Hashimoto’s thyroiditis
proinflammatory
anti-inflammatory nutrients
detoxification
ecological diet
url https://www.mdpi.com/1422-0067/23/9/5144
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AT alexandershinkov nutritionalmanagementofthyroiditisofhashimoto
AT hristogagov nutritionalmanagementofthyroiditisofhashimoto
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