First-trimester urinary extracellular vesicles as predictors of preterm birth: an insight into immune programming

First-trimester urinary extracellular vesicles as predictors of preterm birth: an insight into immune programming

Background: The programming of innate and adaptive immunity plays a pivotal role in determining the course of pregnancy, leading to either normal term birth (TB) or preterm birth (PB) through the modulation of macrophage (M1/M2) differentiation. Extracellular vesicles (EVs) in maternal blood, harbor...

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Bibliographic Details
Main Authors: Jian-Pei Huang, Chia-Hsueh Lin, Chih-Wen Tseng, Ming-Hui Chien, Hung-Chang Lee, Kuender D. Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
preterm birth
first trimester
extracellular vesicles
biomarker
trained immunity
macrophage differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1330049/full

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