Clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniation
Abstract Background Intervertebral disc herniation (IVDH) is the most common spinal cord disease in dogs. Little information is available regarding the clinical presentation of nerve root signature (NRS) associated with cervical IVDH. Hypothesis/Objective To detail the clinical and magnetic resonanc...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-03-01
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| Series: | Journal of Veterinary Internal Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jvim.16982 |
| _version_ | 1827318714558578688 |
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| author | Jordan Schachar Alan Bocage Nathan C. Nelson Peter J. Early Christopher L. Mariani Natasha J. Olby Karen R. Muñana |
| author_facet | Jordan Schachar Alan Bocage Nathan C. Nelson Peter J. Early Christopher L. Mariani Natasha J. Olby Karen R. Muñana |
| author_sort | Jordan Schachar |
| collection | DOAJ |
| description | Abstract Background Intervertebral disc herniation (IVDH) is the most common spinal cord disease in dogs. Little information is available regarding the clinical presentation of nerve root signature (NRS) associated with cervical IVDH. Hypothesis/Objective To detail the clinical and magnetic resonance imaging (MRI) findings in dogs with NRS associated with cervical IVDH. Animals Forty‐seven client‐owned dogs presenting with thoracic limb NRS and MRI confirmed IVDH. Methods Medical records from 2010 to 2020 were retrospectively reviewed for dogs that met inclusion criteria. Imaging studies were evaluated by 2 individuals to characterize location and severity of neural tissue compression. Results Chondrodystrophoid dogs comprised the majority of the study cohort, with dachshund the most common breed (n = 10). Three‐quarters of dogs were ≥7 years of age. Interobserver agreement was moderate or good for all of the imaging variables evaluated. The C6‐C7 intervertebral disc space was significantly overrepresented (P = .01), comprising 32% (15/47) of the affected discs. However, 42% (20/47) of cases involved C2‐C3 though C4‐C5 disc sites. Disc material was more frequently located laterally compared to medially within the vertebral canal (P = .0005), and to be associated with compression of the nerve root at the level of the intervertebral foramen (P = .012). Conclusion/Clinical Importance NRS is most commonly associated with lateralized or foraminal cervical disc herniations. It is most prevalent with C6‐C7 intervertebral disc involvement, suggesting that there might be unique anatomic factors that contribute to development of NRS at this site, but can be a clinical manifestation of IVDH occurring anywhere along the cervical spine. |
| first_indexed | 2024-04-25T00:06:37Z |
| format | Article |
| id | doaj.art-1cf7894830884a3e891b696e6d464471 |
| institution | Directory Open Access Journal |
| issn | 0891-6640 1939-1676 |
| language | English |
| last_indexed | 2024-04-25T00:06:37Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Veterinary Internal Medicine |
| spelling | doaj.art-1cf7894830884a3e891b696e6d4644712024-03-14T04:25:21ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762024-03-013821111111910.1111/jvim.16982Clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniationJordan Schachar0Alan Bocage1Nathan C. Nelson2Peter J. Early3Christopher L. Mariani4Natasha J. Olby5Karen R. Muñana6Department of Clinical Sciences College of Veterinary Medicine, NC State University Raleigh, North Carolina 27606 USADepartment of Molecular and Biomedical Sciences College of Veterinary Medicine, NC State University Raleigh, North Carolina 27606 USADepartment of Molecular and Biomedical Sciences College of Veterinary Medicine, NC State University Raleigh, North Carolina 27606 USADepartment of Clinical Sciences College of Veterinary Medicine, NC State University Raleigh, North Carolina 27606 USADepartment of Clinical Sciences College of Veterinary Medicine, NC State University Raleigh, North Carolina 27606 USADepartment of Clinical Sciences College of Veterinary Medicine, NC State University Raleigh, North Carolina 27606 USADepartment of Clinical Sciences College of Veterinary Medicine, NC State University Raleigh, North Carolina 27606 USAAbstract Background Intervertebral disc herniation (IVDH) is the most common spinal cord disease in dogs. Little information is available regarding the clinical presentation of nerve root signature (NRS) associated with cervical IVDH. Hypothesis/Objective To detail the clinical and magnetic resonance imaging (MRI) findings in dogs with NRS associated with cervical IVDH. Animals Forty‐seven client‐owned dogs presenting with thoracic limb NRS and MRI confirmed IVDH. Methods Medical records from 2010 to 2020 were retrospectively reviewed for dogs that met inclusion criteria. Imaging studies were evaluated by 2 individuals to characterize location and severity of neural tissue compression. Results Chondrodystrophoid dogs comprised the majority of the study cohort, with dachshund the most common breed (n = 10). Three‐quarters of dogs were ≥7 years of age. Interobserver agreement was moderate or good for all of the imaging variables evaluated. The C6‐C7 intervertebral disc space was significantly overrepresented (P = .01), comprising 32% (15/47) of the affected discs. However, 42% (20/47) of cases involved C2‐C3 though C4‐C5 disc sites. Disc material was more frequently located laterally compared to medially within the vertebral canal (P = .0005), and to be associated with compression of the nerve root at the level of the intervertebral foramen (P = .012). Conclusion/Clinical Importance NRS is most commonly associated with lateralized or foraminal cervical disc herniations. It is most prevalent with C6‐C7 intervertebral disc involvement, suggesting that there might be unique anatomic factors that contribute to development of NRS at this site, but can be a clinical manifestation of IVDH occurring anywhere along the cervical spine.https://doi.org/10.1111/jvim.16982cervical radiculopathyintraforaminal disc herniationmagnetic resonance imagingthoracic limb lameness |
| spellingShingle | Jordan Schachar Alan Bocage Nathan C. Nelson Peter J. Early Christopher L. Mariani Natasha J. Olby Karen R. Muñana Clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniation Journal of Veterinary Internal Medicine cervical radiculopathy intraforaminal disc herniation magnetic resonance imaging thoracic limb lameness |
| title | Clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniation |
| title_full | Clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniation |
| title_fullStr | Clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniation |
| title_full_unstemmed | Clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniation |
| title_short | Clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniation |
| title_sort | clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniation |
| topic | cervical radiculopathy intraforaminal disc herniation magnetic resonance imaging thoracic limb lameness |
| url | https://doi.org/10.1111/jvim.16982 |
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