JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryos

The shape and size of the mature central nervous system is highly regular, implying precise architectural rules. The authors show that alterations in JNK signaling in selected neurons impact the overall 3-dimensional organization of the Drosophila ventral nerve cord in a cell non-autonomous fashion.

Bibliographic Details
Main Authors: Katerina Karkali, Timothy E. Saunders, George Panayotou, Enrique Martín-Blanco
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36388-1
Description
Summary:The shape and size of the mature central nervous system is highly regular, implying precise architectural rules. The authors show that alterations in JNK signaling in selected neurons impact the overall 3-dimensional organization of the Drosophila ventral nerve cord in a cell non-autonomous fashion.
ISSN:2041-1723