JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryos
The shape and size of the mature central nervous system is highly regular, implying precise architectural rules. The authors show that alterations in JNK signaling in selected neurons impact the overall 3-dimensional organization of the Drosophila ventral nerve cord in a cell non-autonomous fashion.
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2023-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-36388-1 |
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author | Katerina Karkali Timothy E. Saunders George Panayotou Enrique Martín-Blanco |
author_facet | Katerina Karkali Timothy E. Saunders George Panayotou Enrique Martín-Blanco |
author_sort | Katerina Karkali |
collection | DOAJ |
description | The shape and size of the mature central nervous system is highly regular, implying precise architectural rules. The authors show that alterations in JNK signaling in selected neurons impact the overall 3-dimensional organization of the Drosophila ventral nerve cord in a cell non-autonomous fashion. |
first_indexed | 2024-04-10T15:43:00Z |
format | Article |
id | doaj.art-1cf7f66382af4d7d85478b20b4b0f74c |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-10T15:43:00Z |
publishDate | 2023-02-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-1cf7f66382af4d7d85478b20b4b0f74c2023-02-12T12:16:35ZengNature PortfolioNature Communications2041-17232023-02-0114111610.1038/s41467-023-36388-1JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryosKaterina Karkali0Timothy E. Saunders1George Panayotou2Enrique Martín-Blanco3Instituto de Biología Molecular de Barcelona (CSIC), Parc Cientific de BarcelonaMechanobiology Institute and Department of Biological Sciences, 5 Engineering Drive 1, National University of SingaporeBSRC Alexander FlemingInstituto de Biología Molecular de Barcelona (CSIC), Parc Cientific de BarcelonaThe shape and size of the mature central nervous system is highly regular, implying precise architectural rules. The authors show that alterations in JNK signaling in selected neurons impact the overall 3-dimensional organization of the Drosophila ventral nerve cord in a cell non-autonomous fashion.https://doi.org/10.1038/s41467-023-36388-1 |
spellingShingle | Katerina Karkali Timothy E. Saunders George Panayotou Enrique Martín-Blanco JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryos Nature Communications |
title | JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryos |
title_full | JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryos |
title_fullStr | JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryos |
title_full_unstemmed | JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryos |
title_short | JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryos |
title_sort | jnk signaling in pioneer neurons organizes ventral nerve cord architecture in drosophila embryos |
url | https://doi.org/10.1038/s41467-023-36388-1 |
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