CGRP as a potential mediator for the sexually dimorphic responses to traumatic brain injury

CGRP as a potential mediator for the sexually dimorphic responses to traumatic brain injury

Abstract Background The outcomes of traumatic brain injury (TBI) exhibit variance contingent upon biological sex. Although female sex hormones exert neuroprotective effects, the administration of estrogen and progesterone has not yielded conclusive results. Hence, it is conceivable that additional m...

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Bibliographic Details
Main Authors: Chunyan Li, Erum Ajmal, Khaled Alok, Keren Powell, Steven Wadolowski, Willians Tambo, Justin Turpin, Ernest Barthélemy, Yousef Al-Abed, David LeDoux
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Biology of Sex Differences
Subjects:
Traumatic brain injury
Calcitonin gene-related peptide
Sex hormones
Sexual dimorphism
Oxidative stress
Microvascular dysfunction
Online Access:https://doi.org/10.1186/s13293-024-00619-x

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