Rare adverse effects of anti tuberculous therapy − a case series
Tuberculosis is prevalent throughout the world and is a major public health problem in most developing countries. Standardized and directly observed treatment under NTEP (National Tuberculosis Elimination Programme) is currently recommended for drug-sensitive pulmonary tuberculosis in India. It is g...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | The Journal of Association of Chest Physicians |
| Subjects: | |
| Online Access: | http://www.jacpjournal.org/article.asp?issn=2320-8775;year=2023;volume=11;issue=1;spage=43;epage=49;aulast=Sharma |
| _version_ | 1827896581210243072 |
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| author | Neeraj Sharma Kunal Kumar Sarvinder Singh Puneet Saxena Nalin Singh Akhil Kollammarukudy Ravi |
| author_facet | Neeraj Sharma Kunal Kumar Sarvinder Singh Puneet Saxena Nalin Singh Akhil Kollammarukudy Ravi |
| author_sort | Neeraj Sharma |
| collection | DOAJ |
| description | Tuberculosis is prevalent throughout the world and is a major public health problem in most developing countries. Standardized and directly observed treatment under NTEP (National Tuberculosis Elimination Programme) is currently recommended for drug-sensitive pulmonary tuberculosis in India. It is generally well tolerated, with few minor side effects. Severe side effects necessitating discontinuation of therapy are rare with standard TB treatment regimens. Drug-resistant tuberculosis (DR-TB) has become more common in recent years, posing a challenge to global efforts to control the disease. Therapy for DR-TB has been associated with many adverse effects. Therefore, close monitoring of patients on DR-TB therapy is necessary to ensure that adverse effects of drugs are recognized early by healthcare personnel and treated accordingly. This will improve drug compliance and, hence, treatment goals. Here we report three cases of tuberculosis who had unusual adverse effects while receiving anti-tuberculous medication, prompting drug discontinuation. |
| first_indexed | 2024-03-12T22:37:09Z |
| format | Article |
| id | doaj.art-1cfb6e57ef2d4be5bd299f12d1a5dbea |
| institution | Directory Open Access Journal |
| issn | 2320-8775 2320-9089 |
| language | English |
| last_indexed | 2024-03-12T22:37:09Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Journal of Association of Chest Physicians |
| spelling | doaj.art-1cfb6e57ef2d4be5bd299f12d1a5dbea2023-07-21T11:33:11ZengWolters Kluwer Medknow PublicationsThe Journal of Association of Chest Physicians2320-87752320-90892023-01-01111434910.4103/jacp.jacp_11_22Rare adverse effects of anti tuberculous therapy − a case seriesNeeraj SharmaKunal KumarSarvinder SinghPuneet SaxenaNalin SinghAkhil Kollammarukudy RaviTuberculosis is prevalent throughout the world and is a major public health problem in most developing countries. Standardized and directly observed treatment under NTEP (National Tuberculosis Elimination Programme) is currently recommended for drug-sensitive pulmonary tuberculosis in India. It is generally well tolerated, with few minor side effects. Severe side effects necessitating discontinuation of therapy are rare with standard TB treatment regimens. Drug-resistant tuberculosis (DR-TB) has become more common in recent years, posing a challenge to global efforts to control the disease. Therapy for DR-TB has been associated with many adverse effects. Therefore, close monitoring of patients on DR-TB therapy is necessary to ensure that adverse effects of drugs are recognized early by healthcare personnel and treated accordingly. This will improve drug compliance and, hence, treatment goals. Here we report three cases of tuberculosis who had unusual adverse effects while receiving anti-tuberculous medication, prompting drug discontinuation.http://www.jacpjournal.org/article.asp?issn=2320-8775;year=2023;volume=11;issue=1;spage=43;epage=49;aulast=Sharmaantituberculous therapydrug induced lupusthrombocytopeniatuberculosispancytopenia |
| spellingShingle | Neeraj Sharma Kunal Kumar Sarvinder Singh Puneet Saxena Nalin Singh Akhil Kollammarukudy Ravi Rare adverse effects of anti tuberculous therapy − a case series The Journal of Association of Chest Physicians antituberculous therapy drug induced lupus thrombocytopenia tuberculosis pancytopenia |
| title | Rare adverse effects of anti tuberculous therapy − a case series |
| title_full | Rare adverse effects of anti tuberculous therapy − a case series |
| title_fullStr | Rare adverse effects of anti tuberculous therapy − a case series |
| title_full_unstemmed | Rare adverse effects of anti tuberculous therapy − a case series |
| title_short | Rare adverse effects of anti tuberculous therapy − a case series |
| title_sort | rare adverse effects of anti tuberculous therapy a case series |
| topic | antituberculous therapy drug induced lupus thrombocytopenia tuberculosis pancytopenia |
| url | http://www.jacpjournal.org/article.asp?issn=2320-8775;year=2023;volume=11;issue=1;spage=43;epage=49;aulast=Sharma |
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