Molecular Imaging of Breast Cancer: Present and future directions

Medical imaging technologies have undergone explosive growth over the past few decades and now play a central role in clinical oncology. But the truly transformative power of imaging in the clinical management of cancer patients lies ahead. Today, imaging is at a crossroads, with molecularly targete...

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Main Authors: David eAlcantara, Manuel ePernia Leal, Irene eGarcia, Maria Luisa eGarcia-Martin
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Chemistry
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2014.00112/full
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author David eAlcantara
Manuel ePernia Leal
Irene eGarcia
Maria Luisa eGarcia-Martin
author_facet David eAlcantara
Manuel ePernia Leal
Irene eGarcia
Maria Luisa eGarcia-Martin
author_sort David eAlcantara
collection DOAJ
description Medical imaging technologies have undergone explosive growth over the past few decades and now play a central role in clinical oncology. But the truly transformative power of imaging in the clinical management of cancer patients lies ahead. Today, imaging is at a crossroads, with molecularly targeted imaging agents expected to broadly expand the capabilities of conventional anatomical imaging methods. Molecular imaging will allow clinicians to not only see where a tumour is located in the body, but also to visualize the expression and activity of specific molecules (e.g. proteases and protein kinases) and biological processes (e.g. apoptosis, angiogenesis, and metastasis) that influence tumour behavior and/or response to therapy. Breast cancer, the most common cancer among women and a research area where our group is actively involved, is a very heterogeneous disease with diverse patterns of development and response to treatment. Hence, molecular imaging is expected to have a major impact on this type of cancer, leading to important improvements in diagnosis, individualized treatment, and drug development, as well as our understanding of how breast cancer arises.
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spelling doaj.art-1cfec3c98e994cb69a73001f0ab0e2a52022-12-22T02:10:10ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462014-12-01210.3389/fchem.2014.00112122546Molecular Imaging of Breast Cancer: Present and future directionsDavid eAlcantara0Manuel ePernia Leal1Irene eGarcia2Maria Luisa eGarcia-Martin3Fundacion Publica Andaluza Progreso y SaludFundacion Publica Andaluza Progreso y SaludFundacion Publica Andaluza Progreso y SaludFundacion Publica Andaluza Progreso y SaludMedical imaging technologies have undergone explosive growth over the past few decades and now play a central role in clinical oncology. But the truly transformative power of imaging in the clinical management of cancer patients lies ahead. Today, imaging is at a crossroads, with molecularly targeted imaging agents expected to broadly expand the capabilities of conventional anatomical imaging methods. Molecular imaging will allow clinicians to not only see where a tumour is located in the body, but also to visualize the expression and activity of specific molecules (e.g. proteases and protein kinases) and biological processes (e.g. apoptosis, angiogenesis, and metastasis) that influence tumour behavior and/or response to therapy. Breast cancer, the most common cancer among women and a research area where our group is actively involved, is a very heterogeneous disease with diverse patterns of development and response to treatment. Hence, molecular imaging is expected to have a major impact on this type of cancer, leading to important improvements in diagnosis, individualized treatment, and drug development, as well as our understanding of how breast cancer arises.http://journal.frontiersin.org/Journal/10.3389/fchem.2014.00112/fullbreast cancerbreast cancer diagnosisBreast magnetic resonance imagingMolecular Imaging of breastbreast cancer contrast agentBreast Imaging Techniques
spellingShingle David eAlcantara
Manuel ePernia Leal
Irene eGarcia
Maria Luisa eGarcia-Martin
Molecular Imaging of Breast Cancer: Present and future directions
Frontiers in Chemistry
breast cancer
breast cancer diagnosis
Breast magnetic resonance imaging
Molecular Imaging of breast
breast cancer contrast agent
Breast Imaging Techniques
title Molecular Imaging of Breast Cancer: Present and future directions
title_full Molecular Imaging of Breast Cancer: Present and future directions
title_fullStr Molecular Imaging of Breast Cancer: Present and future directions
title_full_unstemmed Molecular Imaging of Breast Cancer: Present and future directions
title_short Molecular Imaging of Breast Cancer: Present and future directions
title_sort molecular imaging of breast cancer present and future directions
topic breast cancer
breast cancer diagnosis
Breast magnetic resonance imaging
Molecular Imaging of breast
breast cancer contrast agent
Breast Imaging Techniques
url http://journal.frontiersin.org/Journal/10.3389/fchem.2014.00112/full
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AT manuelepernialeal molecularimagingofbreastcancerpresentandfuturedirections
AT ireneegarcia molecularimagingofbreastcancerpresentandfuturedirections
AT marialuisaegarciamartin molecularimagingofbreastcancerpresentandfuturedirections