Lay rescuer use of automated external defibrillators in infants, children and adolescents: A systematic review

Importance: Automated external defibrillator (AED) use is increasing, but use in children is uncommon. A growing literature of use in children by lay rescuers warrants review. Objective: A systematic review of AED effectiveness in children experiencing out-of-hospital cardiac arrest (OHCA). Data Sou...

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Main Authors: Dianne L. Atkins, Jason Acworth, Sung Phil Chung, Amelia Reis, Patrick Van de Voorde
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Resuscitation Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666520422000832
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author Dianne L. Atkins
Jason Acworth
Sung Phil Chung
Amelia Reis
Patrick Van de Voorde
author_facet Dianne L. Atkins
Jason Acworth
Sung Phil Chung
Amelia Reis
Patrick Van de Voorde
author_sort Dianne L. Atkins
collection DOAJ
description Importance: Automated external defibrillator (AED) use is increasing, but use in children is uncommon. A growing literature of use in children by lay rescuers warrants review. Objective: A systematic review of AED effectiveness in children experiencing out-of-hospital cardiac arrest (OHCA). Data Sources: PubMed, EMBASE, Cochrane Register of Controlled Trials. Study Selection: Children, ages 0–18, experiencing OHCA with an AED applied by a lay rescuer. Control population: children with no AED application. Data Extraction and Synthesis: Results are reported according to PRISMA guidelines. Two authors independently reviewed all titles and abstracts of references identified by the search strategy, then generated a subset which all authors reviewed. Main Outcomes and Measures: Critical outcomes were survival with Cerebral Performance Category (CPC) 1–2 at hospital discharge or 30 days and survival to hospital discharge. Results: Population: age categories: <1 year, 1–12 years, 13–18 years. Lay rescuer AED application resulted in improved survival with CPC 1–2 at hospital discharge or 30 days to hospital discharge in age groups 1–12 and 13–18 years (RR 3.84 [95 % CI 2.69–5.5], RR 3.75 [95 %CI 2.97–4.72]), respectively and hospital discharge in both groups(RR 3.04 [95 % CI 2.18–4.25], RR 3.38 [95 % CI 2.17–4.16]), respectively. AED use with CPR improved CPC 1–2 at hospital discharge and hospital discharge (RR 1.49 [95 % CI 1.11–1.97], RR 1.55[1.12–2.12]). Conclusions: AED application by lay rescuers is associated with improved survival with a CPC of 1–2 at 30 days, and improved survival to hospital discharge for children 1–18 years. There are limited data for children < 1 year.
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spelling doaj.art-1cff8b6740c044238cf34b690e951c4e2022-12-22T04:04:42ZengElsevierResuscitation Plus2666-52042022-09-0111100283Lay rescuer use of automated external defibrillators in infants, children and adolescents: A systematic reviewDianne L. Atkins0Jason Acworth1Sung Phil Chung2Amelia Reis3Patrick Van de Voorde4Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA, United States; Corresponding author at: Stead Family Department of Pediatrics, Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, United States.Emergency Department, Queensland Children’s Hospital, Brisbane, Australia; Faculty of Medicine, University of Queensland, AustraliaDepartment of Emergency Medicine, Yonsei University of Medical College, Seoul, Republic of KoreaHospital Das Clinicas, Universidade de Sao Paulo, School of Medicine, BrazilDepartment of Emergency Medicine, Ghent University Hospital, Ghent, Belgium; Federal Department of Health, EMS Dispatch Center, East &amp; West Flanders, BelgiumImportance: Automated external defibrillator (AED) use is increasing, but use in children is uncommon. A growing literature of use in children by lay rescuers warrants review. Objective: A systematic review of AED effectiveness in children experiencing out-of-hospital cardiac arrest (OHCA). Data Sources: PubMed, EMBASE, Cochrane Register of Controlled Trials. Study Selection: Children, ages 0–18, experiencing OHCA with an AED applied by a lay rescuer. Control population: children with no AED application. Data Extraction and Synthesis: Results are reported according to PRISMA guidelines. Two authors independently reviewed all titles and abstracts of references identified by the search strategy, then generated a subset which all authors reviewed. Main Outcomes and Measures: Critical outcomes were survival with Cerebral Performance Category (CPC) 1–2 at hospital discharge or 30 days and survival to hospital discharge. Results: Population: age categories: <1 year, 1–12 years, 13–18 years. Lay rescuer AED application resulted in improved survival with CPC 1–2 at hospital discharge or 30 days to hospital discharge in age groups 1–12 and 13–18 years (RR 3.84 [95 % CI 2.69–5.5], RR 3.75 [95 %CI 2.97–4.72]), respectively and hospital discharge in both groups(RR 3.04 [95 % CI 2.18–4.25], RR 3.38 [95 % CI 2.17–4.16]), respectively. AED use with CPR improved CPC 1–2 at hospital discharge and hospital discharge (RR 1.49 [95 % CI 1.11–1.97], RR 1.55[1.12–2.12]). Conclusions: AED application by lay rescuers is associated with improved survival with a CPC of 1–2 at 30 days, and improved survival to hospital discharge for children 1–18 years. There are limited data for children < 1 year.http://www.sciencedirect.com/science/article/pii/S2666520422000832Public access defibrillationOut-of-hospital cardiac arrestDefibrillationCardiopulmonary resuscitationChildrenAdolescent
spellingShingle Dianne L. Atkins
Jason Acworth
Sung Phil Chung
Amelia Reis
Patrick Van de Voorde
Lay rescuer use of automated external defibrillators in infants, children and adolescents: A systematic review
Resuscitation Plus
Public access defibrillation
Out-of-hospital cardiac arrest
Defibrillation
Cardiopulmonary resuscitation
Children
Adolescent
title Lay rescuer use of automated external defibrillators in infants, children and adolescents: A systematic review
title_full Lay rescuer use of automated external defibrillators in infants, children and adolescents: A systematic review
title_fullStr Lay rescuer use of automated external defibrillators in infants, children and adolescents: A systematic review
title_full_unstemmed Lay rescuer use of automated external defibrillators in infants, children and adolescents: A systematic review
title_short Lay rescuer use of automated external defibrillators in infants, children and adolescents: A systematic review
title_sort lay rescuer use of automated external defibrillators in infants children and adolescents a systematic review
topic Public access defibrillation
Out-of-hospital cardiac arrest
Defibrillation
Cardiopulmonary resuscitation
Children
Adolescent
url http://www.sciencedirect.com/science/article/pii/S2666520422000832
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