Chemometrics-based evaluation on the effect of sonication, contact time and solid-to-solvent ratio on total phenolics and flavonoids, free fatty acids and antibacterial potency of Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilis
This study was aimed at extraction optimization of antibacterial agents from Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilis as affected by sonication-assisted extraction (SAE), contact time (CT) and solid-to-solvent ratio (SSR). The principal component analysis...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-10-01
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| Series: | Food Chemistry Advances |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772753X22000211 |
| _version_ | 1811187175898742784 |
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| author | Muhamad Shirwan Abdullah Sani Jamilah Bakar Azman Azid Muhammad Javid Iqbal |
| author_facet | Muhamad Shirwan Abdullah Sani Jamilah Bakar Azman Azid Muhammad Javid Iqbal |
| author_sort | Muhamad Shirwan Abdullah Sani |
| collection | DOAJ |
| description | This study was aimed at extraction optimization of antibacterial agents from Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilis as affected by sonication-assisted extraction (SAE), contact time (CT) and solid-to-solvent ratio (SSR). The principal component analysis (PCA) and individual evaluation approaches identified that no SAE, 8 CT and 1:10 SSR were the best treatments with the highest antibacterial potency. The PCA identified no SAE, 8 CT, and 1:5 SSR as the second-beat treatment. The yield, total phenolic compound (TPC), C18:1n9t and C16:1 free fatty acids (FAs) in no SAE, 8 CT and 1:10 SSR treatment inhibited B. cereus, V. vulnificus and P. mirabilis growths while C21:0 and C15:0 in 30 min SAE, 8 CT and 1:2 SSR inhibited S. enteritidis growth. The yield, TPC, C18:1n9t and C16:1 FAs, and C6:0 and C24:1n9, C20:1, C4:0 and C20:0 FAs had antagonistic effects on B. cereus, V. vulnificus and P. mirabilis growths. The C21:0, C15:0, C6:0 and C13:0, and C23:0, C20:0 and C11:0 FAs had antagonistic effects on S. enteritidis growth. The PCA also denoted that the MIC50 and MIC0 had a higher variation than MIC; hence, the former variables were better to use in PCA. |
| first_indexed | 2024-04-11T13:58:56Z |
| format | Article |
| id | doaj.art-1d02f8c9f9784ba6b4d042ebff495765 |
| institution | Directory Open Access Journal |
| issn | 2772-753X |
| language | English |
| last_indexed | 2024-04-11T13:58:56Z |
| publishDate | 2022-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry Advances |
| spelling | doaj.art-1d02f8c9f9784ba6b4d042ebff4957652022-12-22T04:20:11ZengElsevierFood Chemistry Advances2772-753X2022-10-011100033Chemometrics-based evaluation on the effect of sonication, contact time and solid-to-solvent ratio on total phenolics and flavonoids, free fatty acids and antibacterial potency of Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilisMuhamad Shirwan Abdullah Sani0Jamilah Bakar1Azman Azid2Muhammad Javid Iqbal3International Institute for Halal Research and Training, International Islamic University Malaysia (IIUM), Level 3, KICT Building, Kuala Lumpur 53100, Malaysia; Federal Government Administrative Center, Ministry of Higher Education, Konsortium Institut Halal IPT Malaysia, Block E8, Complex E, Putrajaya 62604, Malaysia; The Catalytixs Solutions, No. 713, Jalan DPP ¼, Desa Permai Pedas, Pedas, Negeri Sembilan 71400, Malaysia; Corresponding author at: International Institute for Halal Research and Training, International Islamic University Malaysia (IIUM), Level 3, KICT Building, Kuala Lumpur 53100, Malaysia.Department of Food Technology, Faculty of Food Science and Technology, Universiti Putra Malaysia, Serdang, Selangor 43400, MalaysiaFaculty of Bioresources and Food Industry, Universiti Sultan Zainal Abidin (UniSZA), Besut, Terengganu 22200, MalaysiaDepartment of Chemistry, COMSATS University Islamabad, Lahore Campus, PakistanThis study was aimed at extraction optimization of antibacterial agents from Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilis as affected by sonication-assisted extraction (SAE), contact time (CT) and solid-to-solvent ratio (SSR). The principal component analysis (PCA) and individual evaluation approaches identified that no SAE, 8 CT and 1:10 SSR were the best treatments with the highest antibacterial potency. The PCA identified no SAE, 8 CT, and 1:5 SSR as the second-beat treatment. The yield, total phenolic compound (TPC), C18:1n9t and C16:1 free fatty acids (FAs) in no SAE, 8 CT and 1:10 SSR treatment inhibited B. cereus, V. vulnificus and P. mirabilis growths while C21:0 and C15:0 in 30 min SAE, 8 CT and 1:2 SSR inhibited S. enteritidis growth. The yield, TPC, C18:1n9t and C16:1 FAs, and C6:0 and C24:1n9, C20:1, C4:0 and C20:0 FAs had antagonistic effects on B. cereus, V. vulnificus and P. mirabilis growths. The C21:0, C15:0, C6:0 and C13:0, and C23:0, C20:0 and C11:0 FAs had antagonistic effects on S. enteritidis growth. The PCA also denoted that the MIC50 and MIC0 had a higher variation than MIC; hence, the former variables were better to use in PCA.http://www.sciencedirect.com/science/article/pii/S2772753X22000211Sonication-assisted extractionContact timeSolid-to-solvent ratioAntibacterial potencyCarica papaya seed |
| spellingShingle | Muhamad Shirwan Abdullah Sani Jamilah Bakar Azman Azid Muhammad Javid Iqbal Chemometrics-based evaluation on the effect of sonication, contact time and solid-to-solvent ratio on total phenolics and flavonoids, free fatty acids and antibacterial potency of Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilis Food Chemistry Advances Sonication-assisted extraction Contact time Solid-to-solvent ratio Antibacterial potency Carica papaya seed |
| title | Chemometrics-based evaluation on the effect of sonication, contact time and solid-to-solvent ratio on total phenolics and flavonoids, free fatty acids and antibacterial potency of Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilis |
| title_full | Chemometrics-based evaluation on the effect of sonication, contact time and solid-to-solvent ratio on total phenolics and flavonoids, free fatty acids and antibacterial potency of Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilis |
| title_fullStr | Chemometrics-based evaluation on the effect of sonication, contact time and solid-to-solvent ratio on total phenolics and flavonoids, free fatty acids and antibacterial potency of Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilis |
| title_full_unstemmed | Chemometrics-based evaluation on the effect of sonication, contact time and solid-to-solvent ratio on total phenolics and flavonoids, free fatty acids and antibacterial potency of Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilis |
| title_short | Chemometrics-based evaluation on the effect of sonication, contact time and solid-to-solvent ratio on total phenolics and flavonoids, free fatty acids and antibacterial potency of Carica papaya seed against S. enteritidis, B. cereus, V. vulnificus and P. mirabilis |
| title_sort | chemometrics based evaluation on the effect of sonication contact time and solid to solvent ratio on total phenolics and flavonoids free fatty acids and antibacterial potency of carica papaya seed against s enteritidis b cereus v vulnificus and p mirabilis |
| topic | Sonication-assisted extraction Contact time Solid-to-solvent ratio Antibacterial potency Carica papaya seed |
| url | http://www.sciencedirect.com/science/article/pii/S2772753X22000211 |
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