BMSC-derived exosomes promote tendon-bone healing after anterior cruciate ligament reconstruction by regulating M1/M2 macrophage polarization in rats

BMSC-derived exosomes promote tendon-bone healing after anterior cruciate ligament reconstruction by regulating M1/M2 macrophage polarization in rats

Abstract Background Recent studies have shown that bone marrow stromal cell-derived exosomes (BMSC-Exos) can be used for tissue repair. However, whether the BMSC-Exos can promote tendon-bone healing after anterior cruciate ligament reconstruction (ACLR) is still unclear. In this study, we observed i...

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Bibliographic Details
Main Authors:	Zhenyu Li, Qingxian Li, Kai Tong, Jiayong Zhu, Hui Wang, Biao Chen, Liaobin Chen
Format:	Article
Language:	English
Published:	BMC 2022-07-01
Series:	Stem Cell Research & Therapy
Subjects:	Bone marrow stromal cell Exosome Macrophage polarization Tendon-bone healing miRNA
Online Access:	https://doi.org/10.1186/s13287-022-02975-0

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