Application of simple fed-batch technique to high-level secretory production of insulin precursor using <it>Pichia pastoris </it>with subsequent purification and conversion to human insulin

Application of simple fed-batch technique to high-level secretory production of insulin precursor using <it>Pichia pastoris </it>with subsequent purification and conversion to human insulin

<p>Abstract</p> <p>Background</p> <p>The prevalence of diabetes is predicted to rise significantly in the coming decades. A recent analysis projects that by the year 2030 there will be ~366 million diabetics around the world, leading to an increased demand for inexpensi...

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Bibliographic Details
Main Authors: Chugh Dipti, Gäbel Thomas, Adnan Ahmad, Skoko Natasa, Polez Sulena, Gurramkonda Chandrasekhar, Swaminathan Sathyamangalam, Khanna Navin, Tisminetzky Sergio, Rinas Ursula
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/9/1/31

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