Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions?
Abstract Background Dynamic contrast-enhanced MRI of the breast has been used for several years in the assessment of indeterminate mammographic findings. Contrast-enhanced mammography is a relatively novel imaging technique that has shown comparable sensitivity and specificity to MRI. Contrast-enhan...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2020-04-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s43055-020-00188-0 |
| _version_ | 1818882778504101888 |
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| author | Rasha Mohamed Kamal Mennatallah Mohamed Hanafy Sahar Mahmoud Mansour Maher Hassan Mohamed Mohamed Gomaa |
| author_facet | Rasha Mohamed Kamal Mennatallah Mohamed Hanafy Sahar Mahmoud Mansour Maher Hassan Mohamed Mohamed Gomaa |
| author_sort | Rasha Mohamed Kamal |
| collection | DOAJ |
| description | Abstract Background Dynamic contrast-enhanced MRI of the breast has been used for several years in the assessment of indeterminate mammographic findings. Contrast-enhanced mammography is a relatively novel imaging technique that has shown comparable sensitivity and specificity to MRI. Contrast-enhanced mammography is a relatively easy feasible study with high sensitivity and low cost. Our aim was to assess the feasibility of replacing dynamic contrast-enhanced (DCE)-MRI by contrast-enhanced mammography in the assessment of sonomammographic indeterminate lesions (BIRADS 3 and 4). Results The study included 82 patients with 171 breast lesions. They all performed contrast-enhanced mammography and dynamic contrast-enhanced MRI. DCE-MRI sensitivity and NPV were significantly higher than those of contrast-enhanced mammogram (CEM). The overall accuracy of MRI was better than that of CEM; however, no statistically significant difference could be detected. Conclusion Contrast-enhanced mammography and dynamic contrast-enhanced MRI improved the characterization of breast lesions. CEM showed slightly lower sensitivity and accuracy compared to MRI; however, because of being relatively easy, available, cheap, and acceptable by women, CEM can replace DC-MRI as a problem-solving tool in the characterization of indeterminate breast lesions. |
| first_indexed | 2024-12-19T15:23:10Z |
| format | Article |
| id | doaj.art-1d0cae08d2294fa88adb6f152d508043 |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-12-19T15:23:10Z |
| publishDate | 2020-04-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-1d0cae08d2294fa88adb6f152d5080432022-12-21T20:15:57ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622020-04-015111810.1186/s43055-020-00188-0Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions?Rasha Mohamed Kamal0Mennatallah Mohamed Hanafy1Sahar Mahmoud Mansour2Maher Hassan3Mohamed Mohamed Gomaa4Department of Diagnostic and Interventional Radiology, Faculty of Medicine, Cairo UniversityDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Cairo UniversityDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Cairo UniversityDepartment of Surgical Oncology, National Cancer Institute, Cairo UniversityDepartment of Diagnostic and Interventional Radiology, National Cancer Institute, Cairo UniversityAbstract Background Dynamic contrast-enhanced MRI of the breast has been used for several years in the assessment of indeterminate mammographic findings. Contrast-enhanced mammography is a relatively novel imaging technique that has shown comparable sensitivity and specificity to MRI. Contrast-enhanced mammography is a relatively easy feasible study with high sensitivity and low cost. Our aim was to assess the feasibility of replacing dynamic contrast-enhanced (DCE)-MRI by contrast-enhanced mammography in the assessment of sonomammographic indeterminate lesions (BIRADS 3 and 4). Results The study included 82 patients with 171 breast lesions. They all performed contrast-enhanced mammography and dynamic contrast-enhanced MRI. DCE-MRI sensitivity and NPV were significantly higher than those of contrast-enhanced mammogram (CEM). The overall accuracy of MRI was better than that of CEM; however, no statistically significant difference could be detected. Conclusion Contrast-enhanced mammography and dynamic contrast-enhanced MRI improved the characterization of breast lesions. CEM showed slightly lower sensitivity and accuracy compared to MRI; however, because of being relatively easy, available, cheap, and acceptable by women, CEM can replace DC-MRI as a problem-solving tool in the characterization of indeterminate breast lesions.http://link.springer.com/article/10.1186/s43055-020-00188-0Contrast-enhanced mammogramDynamic contrast-enhanced MRIindeterminate breast lesions |
| spellingShingle | Rasha Mohamed Kamal Mennatallah Mohamed Hanafy Sahar Mahmoud Mansour Maher Hassan Mohamed Mohamed Gomaa Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions? The Egyptian Journal of Radiology and Nuclear Medicine Contrast-enhanced mammogram Dynamic contrast-enhanced MRI indeterminate breast lesions |
| title | Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions? |
| title_full | Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions? |
| title_fullStr | Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions? |
| title_full_unstemmed | Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions? |
| title_short | Can contrast-enhanced mammography replace dynamic contrast-enhanced MRI in the assessment of sonomammographic indeterminate breast lesions? |
| title_sort | can contrast enhanced mammography replace dynamic contrast enhanced mri in the assessment of sonomammographic indeterminate breast lesions |
| topic | Contrast-enhanced mammogram Dynamic contrast-enhanced MRI indeterminate breast lesions |
| url | http://link.springer.com/article/10.1186/s43055-020-00188-0 |
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