Research progress in colitis-induced hepatic barrier dysfunction
Liver barrier functions as a main structure to protect the liver from exogenous harmful substances and play an important role in maintaining secretion function, regulating bile transport and intercellular information transmission. Liver barrier protein alteration and barrier dysfunction can be induc...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2022-01-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-149.pdf |
| _version_ | 1797365904422469632 |
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| author | SHU Meng-xuan, YUAN Fang-chen, ZHOU Meng-qi, TU Shi-yan, XU Yue, QIN Hong-yan |
| author_facet | SHU Meng-xuan, YUAN Fang-chen, ZHOU Meng-qi, TU Shi-yan, XU Yue, QIN Hong-yan |
| author_sort | SHU Meng-xuan, YUAN Fang-chen, ZHOU Meng-qi, TU Shi-yan, XU Yue, QIN Hong-yan |
| collection | DOAJ |
| description | Liver barrier functions as a main structure to protect the liver from exogenous harmful substances and play an important role in maintaining secretion function, regulating bile transport and intercellular information transmission. Liver barrier protein alteration and barrier dysfunction can be induced by endotoxin, inflammatory cytokines and bile acids, which may be involved in the occurrence of colitis-related liver diseases. To explore the outcomes and underlying mechanism of intestinal inflammation on liver barrier function may support the understanding of pathogenesis of colitis-related liver diseases and thus provide clues and basic information for the prevention and treatment of colitis-related liver diseases. |
| first_indexed | 2024-03-08T16:55:35Z |
| format | Article |
| id | doaj.art-1d0d124c740b41cfa031e7f4033309d7 |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T16:55:35Z |
| publishDate | 2022-01-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-1d0d124c740b41cfa031e7f4033309d72024-01-05T02:33:55ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252022-01-0142114915310.16352/j.issn.1001-6325.2022.01.022Research progress in colitis-induced hepatic barrier dysfunctionSHU Meng-xuan, YUAN Fang-chen, ZHOU Meng-qi, TU Shi-yan, XU Yue, QIN Hong-yan01. Department of Pharmacy, the First Hospital of Lanzhou University, Lanzhou 730000;;2. the First Clinical Medical College, Lanzhou University, Lanzhou 730000, ChinaLiver barrier functions as a main structure to protect the liver from exogenous harmful substances and play an important role in maintaining secretion function, regulating bile transport and intercellular information transmission. Liver barrier protein alteration and barrier dysfunction can be induced by endotoxin, inflammatory cytokines and bile acids, which may be involved in the occurrence of colitis-related liver diseases. To explore the outcomes and underlying mechanism of intestinal inflammation on liver barrier function may support the understanding of pathogenesis of colitis-related liver diseases and thus provide clues and basic information for the prevention and treatment of colitis-related liver diseases.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-149.pdfcolitis|liver barrier|endotoxin|bile acids|inflammatory cytokines |
| spellingShingle | SHU Meng-xuan, YUAN Fang-chen, ZHOU Meng-qi, TU Shi-yan, XU Yue, QIN Hong-yan Research progress in colitis-induced hepatic barrier dysfunction Jichu yixue yu linchuang colitis|liver barrier|endotoxin|bile acids|inflammatory cytokines |
| title | Research progress in colitis-induced hepatic barrier dysfunction |
| title_full | Research progress in colitis-induced hepatic barrier dysfunction |
| title_fullStr | Research progress in colitis-induced hepatic barrier dysfunction |
| title_full_unstemmed | Research progress in colitis-induced hepatic barrier dysfunction |
| title_short | Research progress in colitis-induced hepatic barrier dysfunction |
| title_sort | research progress in colitis induced hepatic barrier dysfunction |
| topic | colitis|liver barrier|endotoxin|bile acids|inflammatory cytokines |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-149.pdf |
| work_keys_str_mv | AT shumengxuanyuanfangchenzhoumengqitushiyanxuyueqinhongyan researchprogressincolitisinducedhepaticbarrierdysfunction |