Microscale Thermophoresis and Molecular Modelling to Explore the Chelating Drug Transportation in the Milk to Infant

Microscale Thermophoresis and Molecular Modelling to Explore the Chelating Drug Transportation in the Milk to Infant

The microscale thermophoresis (MST) technique was utilized to investigate lactoferrin–drug interaction with the iron chelator, deferiprone, using label-free system. MST depends on the intrinsic fluorescence of one interacting partner. The results indicated a significant interaction between lactoferr...

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Bibliographic Details
Main Authors: Mufarreh Asmari, Muhammad Waqas, Adel Ehab Ibrahim, Sobia Ahsan Halim, Ajmal Khan, Ahmed Al-Harrasi, Hermann Wätzig, Sami El Deeb
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
microscale thermophoresis
lactoferrin
deferiprone
dissociation constant
molecular modeling
Online Access:https://www.mdpi.com/1420-3049/27/14/4604

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