Serum Lipids and Diabetic Retinopathy in Newly Diagnosed Type 2 Diabetic Subjects
Background: Diabetic retinopathy is the commonest and usually the first observable vascular complication of diabetes mellitus. Along with hyperglycaemia, dyslipidaemia is a contributing factor for the occurrence of diabetic retinopathy. It is postulated that dyslipidaemia results in formation of har...
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| Format: | Article |
| Language: | English |
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Enam Medical College, Dhaka
2011-07-01
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| Series: | Journal of Enam Medical College |
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| Online Access: | http://banglajol.info/index.php/JEMC/article/view/11464 |
| _version_ | 1818791590480576512 |
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| author | Shahana Shermin Forhadul Hoque Mollah Md Mozammel Hoque M Iqbal Arslan Md Rezwanur Rahman |
| author_facet | Shahana Shermin Forhadul Hoque Mollah Md Mozammel Hoque M Iqbal Arslan Md Rezwanur Rahman |
| author_sort | Shahana Shermin |
| collection | DOAJ |
| description | Background: Diabetic retinopathy is the commonest and usually the first observable vascular complication of diabetes mellitus. Along with hyperglycaemia, dyslipidaemia is a contributing factor for the occurrence of diabetic retinopathy. It is postulated that dyslipidaemia results in formation of hard exudate by increasing blood viscosity and altering the fibrinolytic system. A case control study was carried out in the department of Biochemistry, Bangabandhu Sheikh Mujib Medical University, Dhaka during the period of January 2006 to December 2007 to evaluate the serum lipid profile in newly diagnosed type 2 diabetic subjects with diabetic retinopathy. Materials and Methods: Total 85 newly diagnosed type 2 diabetic subjects were included in this study, 40 were cases having retinopathy and 45 were age and sex matched controls without retinopathy. Serum triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were compared between cases and controls. Unpaired t-test and chi-square test were done between groups as tests of significance. Results: All the parameters of lipid profile showed dyslipidaemic trend both in cases and controls. In the cases TG was significantly higher and HDL-C was significantly lower than that of controls (p < 0.05) whereas no significant difference was found between cases and controls with respect to serum TC and LDL-C. Conclusion: It can be concluded that high TG and low HDL-C are associated with diabetic retinopathy in newly diagnosed type 2 diabetes. |
| first_indexed | 2024-12-18T15:13:46Z |
| format | Article |
| id | doaj.art-1d0db6fd00ea4f5f8b7393c0a6296614 |
| institution | Directory Open Access Journal |
| issn | 2227-6688 2304-9316 |
| language | English |
| last_indexed | 2024-12-18T15:13:46Z |
| publishDate | 2011-07-01 |
| publisher | Enam Medical College, Dhaka |
| record_format | Article |
| series | Journal of Enam Medical College |
| spelling | doaj.art-1d0db6fd00ea4f5f8b7393c0a62966142022-12-21T21:03:35ZengEnam Medical College, DhakaJournal of Enam Medical College2227-66882304-93162011-07-01126366Lipid profile; Dyslipidaemia; Diabetic retinopathySerum Lipids and Diabetic Retinopathy in Newly Diagnosed Type 2 Diabetic SubjectsShahana SherminForhadul Hoque MollahMd Mozammel HoqueM Iqbal ArslanMd Rezwanur RahmanBackground: Diabetic retinopathy is the commonest and usually the first observable vascular complication of diabetes mellitus. Along with hyperglycaemia, dyslipidaemia is a contributing factor for the occurrence of diabetic retinopathy. It is postulated that dyslipidaemia results in formation of hard exudate by increasing blood viscosity and altering the fibrinolytic system. A case control study was carried out in the department of Biochemistry, Bangabandhu Sheikh Mujib Medical University, Dhaka during the period of January 2006 to December 2007 to evaluate the serum lipid profile in newly diagnosed type 2 diabetic subjects with diabetic retinopathy. Materials and Methods: Total 85 newly diagnosed type 2 diabetic subjects were included in this study, 40 were cases having retinopathy and 45 were age and sex matched controls without retinopathy. Serum triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were compared between cases and controls. Unpaired t-test and chi-square test were done between groups as tests of significance. Results: All the parameters of lipid profile showed dyslipidaemic trend both in cases and controls. In the cases TG was significantly higher and HDL-C was significantly lower than that of controls (p < 0.05) whereas no significant difference was found between cases and controls with respect to serum TC and LDL-C. Conclusion: It can be concluded that high TG and low HDL-C are associated with diabetic retinopathy in newly diagnosed type 2 diabetes.http://banglajol.info/index.php/JEMC/article/view/11464Lipid profileDyslipidaemiaDiabetic retinopathy |
| spellingShingle | Shahana Shermin Forhadul Hoque Mollah Md Mozammel Hoque M Iqbal Arslan Md Rezwanur Rahman Serum Lipids and Diabetic Retinopathy in Newly Diagnosed Type 2 Diabetic Subjects Journal of Enam Medical College Lipid profile Dyslipidaemia Diabetic retinopathy |
| title | Serum Lipids and Diabetic Retinopathy in Newly Diagnosed Type 2 Diabetic Subjects |
| title_full | Serum Lipids and Diabetic Retinopathy in Newly Diagnosed Type 2 Diabetic Subjects |
| title_fullStr | Serum Lipids and Diabetic Retinopathy in Newly Diagnosed Type 2 Diabetic Subjects |
| title_full_unstemmed | Serum Lipids and Diabetic Retinopathy in Newly Diagnosed Type 2 Diabetic Subjects |
| title_short | Serum Lipids and Diabetic Retinopathy in Newly Diagnosed Type 2 Diabetic Subjects |
| title_sort | serum lipids and diabetic retinopathy in newly diagnosed type 2 diabetic subjects |
| topic | Lipid profile Dyslipidaemia Diabetic retinopathy |
| url | http://banglajol.info/index.php/JEMC/article/view/11464 |
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