REGULARITIES OF СOMPENSATORY-ADAPTIVE REACTIONS IMMUNE RESPONSE OF WORKERS IN CHRONIC EXPOSURE TO VINYL CHLORIDE
Laboratory and immunological study of male workers in the production of vinyl chloride was conducted. It has established that more pronounced stress of compensatory-adaptive reactions is observed in patients with incipient neurointoxication ("at risk”) in comparison to group of ‘healthy”. With...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2012-05-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/882 |
| Summary: | Laboratory and immunological study of male workers in the production of vinyl chloride was conducted. It has established that more pronounced stress of compensatory-adaptive reactions is observed in patients with incipient neurointoxication ("at risk”) in comparison to group of ‘healthy”. With increasing radiation exposure to vinyl chloride, duration (length of) exposure, as well as increasing the concentration of chloride in the blood, showed worsening of changes in the immune system of workers. Installed elevated levels of autoantibodies: the S-100, B-head. Ca-channel and the DNA appear to be indicative of early changes in certain structures of the nervous system. Some of the earliest and most sensitive indicators of the formation of body resistance to unfavorable working environment are: IgM, IL-1β, TNF-α, IL-8, autoantibodies to S-100, autoantibodies to the В-head. Ca-channel, autoantibodies to DNA. |
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| ISSN: | 2541-9420 2587-9596 |