The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran
Increasing microbial resistance is a severe threat to global public health. One of the most common diseases in the intensive care unit is ventilator-associated pneumonia. This study was carried out from January to March 2018, at the Golestan Hospital of Ahvaz. Patients with ventilator-associated pne...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Research Center for Rational Use of Drugs (RCRUD)
2020-06-01
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| Series: | Journal of Pharmaceutical Care |
| Subjects: | |
| Online Access: | https://jpc.tums.ac.ir/index.php/jpc/article/view/295 |
| _version_ | 1819006039900553216 |
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| author | Saeed Mehralinejadian Mandana Izadpanah Farhad Soltani Sepideh Sayadi Maryam Aghakouchakzadeh |
| author_facet | Saeed Mehralinejadian Mandana Izadpanah Farhad Soltani Sepideh Sayadi Maryam Aghakouchakzadeh |
| author_sort | Saeed Mehralinejadian |
| collection | DOAJ |
| description | Increasing microbial resistance is a severe threat to global public health. One of the most common diseases in the intensive care unit is ventilator-associated pneumonia. This study was carried out from January to March 2018, at the Golestan Hospital of Ahvaz. Patients with ventilator-associated pneumonia were included in the study. The prevalence of resistant gram-negative microorganisms was studied through reported laboratory antibiogram results of cultures.
Based on the results of the study, From 373 hospitalized patients, 38 (10.2%) were diagnosed with VAP. From the 57 respiratory cultures performed, overall 90 microorganisms were isolated, from which Enterobacter with 36 cases (39.5%) and E.Coli with 28 cases (30.7%) was most frequently compared to other organisms. Of the 90 organisms responsible for the infection, 43 cases (47.2%) were MDR microorganisms and 47 (51.6%) were XDR microorganisms. Enterobacter and E.Coli were the most prevalent MDR microorganisms with 17 cases (39.5%) and 13 (30.2%), respectively. Also, these two microorganisms were the most abundant XDR microorganisms with 19 cases (40.4%) and 15 (31.9%), respectively.
The results show the requirement of robust antibiotic monitoring and the optimization of antibiotic use in order to prevent the progression of antibiotic resistance in these units. |
| first_indexed | 2024-12-21T00:02:21Z |
| format | Article |
| id | doaj.art-1d13975acd3a4e43a7993a2c36ef184d |
| institution | Directory Open Access Journal |
| issn | 2322-4630 2322-4509 |
| language | English |
| last_indexed | 2024-12-21T00:02:21Z |
| publishDate | 2020-06-01 |
| publisher | Research Center for Rational Use of Drugs (RCRUD) |
| record_format | Article |
| series | Journal of Pharmaceutical Care |
| spelling | doaj.art-1d13975acd3a4e43a7993a2c36ef184d2022-12-21T19:22:35ZengResearch Center for Rational Use of Drugs (RCRUD)Journal of Pharmaceutical Care2322-46302322-45092020-06-018387295The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of IranSaeed MehralinejadianMandana IzadpanahFarhad SoltaniSepideh SayadiMaryam AghakouchakzadehIncreasing microbial resistance is a severe threat to global public health. One of the most common diseases in the intensive care unit is ventilator-associated pneumonia. This study was carried out from January to March 2018, at the Golestan Hospital of Ahvaz. Patients with ventilator-associated pneumonia were included in the study. The prevalence of resistant gram-negative microorganisms was studied through reported laboratory antibiogram results of cultures. Based on the results of the study, From 373 hospitalized patients, 38 (10.2%) were diagnosed with VAP. From the 57 respiratory cultures performed, overall 90 microorganisms were isolated, from which Enterobacter with 36 cases (39.5%) and E.Coli with 28 cases (30.7%) was most frequently compared to other organisms. Of the 90 organisms responsible for the infection, 43 cases (47.2%) were MDR microorganisms and 47 (51.6%) were XDR microorganisms. Enterobacter and E.Coli were the most prevalent MDR microorganisms with 17 cases (39.5%) and 13 (30.2%), respectively. Also, these two microorganisms were the most abundant XDR microorganisms with 19 cases (40.4%) and 15 (31.9%), respectively. The results show the requirement of robust antibiotic monitoring and the optimization of antibiotic use in order to prevent the progression of antibiotic resistance in these units.https://jpc.tums.ac.ir/index.php/jpc/article/view/295resistanceventilator-associated pneumoniaintensive care unitsgram-negative microorganisms |
| spellingShingle | Saeed Mehralinejadian Mandana Izadpanah Farhad Soltani Sepideh Sayadi Maryam Aghakouchakzadeh The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran Journal of Pharmaceutical Care resistance ventilator-associated pneumonia intensive care units gram-negative microorganisms |
| title | The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran |
| title_full | The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran |
| title_fullStr | The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran |
| title_full_unstemmed | The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran |
| title_short | The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran |
| title_sort | prevalence of gram negative microorganisms isolated from ventilatorassociated pneumonia patients in the intensive care units of southwest of iran |
| topic | resistance ventilator-associated pneumonia intensive care units gram-negative microorganisms |
| url | https://jpc.tums.ac.ir/index.php/jpc/article/view/295 |
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