Biomechanical analysis of customized cage conforming to the endplate morphology in anterior cervical discectomy fusion: A finite element analysis
In anterior cervical discectomy and fusion (ACDF), an interbody fusion device is an essential implant. An unsuitable interbody fusion device can cause postoperative complications, including subsidence and nonunion. We designed a customized intervertebral fusion device to reduce postoperative complic...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023001305 |
| _version_ | 1811173326616264704 |
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| author | Bin Sun Qing Han FengXu Sui AoBo Zhang Yang Liu Peng Xia JinCheng Wang XiaoYu Yang |
| author_facet | Bin Sun Qing Han FengXu Sui AoBo Zhang Yang Liu Peng Xia JinCheng Wang XiaoYu Yang |
| author_sort | Bin Sun |
| collection | DOAJ |
| description | In anterior cervical discectomy and fusion (ACDF), an interbody fusion device is an essential implant. An unsuitable interbody fusion device can cause postoperative complications, including subsidence and nonunion. We designed a customized intervertebral fusion device to reduce postoperative complications and validated it by finite element analysis. Herein, we built a non-homogeneous model of the C3-7 cervical spine. Three implant models (customized cage, commercial cage, and bone graft cage) were constructed and placed in the C45 cervical segment after ACDF surgery. The simulated range of motion (ROM), stress at the cage-bone interface, and stress on the cage and implants were compared under different conditions. The commercial cage showed maximum stress peaks at 40.3 MPa and 43.2 MPa in the inferior endplate of C4 and superior endplate of C5 under rotational conditions, higher compared to 29.7 MPa and 26.4 MPa, respectively, in the customized cage. The ROM was not significantly different between the three cages placed after ACDF. The stresses on the commercial cage were higher compared to the other two cages under all conditions. The bone graft in the customized cage was subject to higher stress than the commercial cage under all conditions, particularly lateral bending, wherein the maximum stress was 5.5 MPa. These results showed that a customized cage that better conformed to the vertebral anatomy was promising for reducing the risk of stress shielding and the occurrence of subsidence. |
| first_indexed | 2024-04-10T17:45:04Z |
| format | Article |
| id | doaj.art-1d14317a87e043dc80d519f3f97eefc0 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-10T17:45:04Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-1d14317a87e043dc80d519f3f97eefc02023-02-03T04:59:44ZengElsevierHeliyon2405-84402023-01-0191e12923Biomechanical analysis of customized cage conforming to the endplate morphology in anterior cervical discectomy fusion: A finite element analysisBin Sun0Qing Han1FengXu Sui2AoBo Zhang3Yang Liu4Peng Xia5JinCheng Wang6XiaoYu Yang7Department of Orthopedics, The Second Hospital of Jilin University, No. 218 Ziqiang Street, 130041, Changchun, Jilin, ChinaDepartment of Orthopedics, The Second Hospital of Jilin University, No. 218 Ziqiang Street, 130041, Changchun, Jilin, ChinaDepartment of Orthopedics, The Second Hospital of Jilin University, No. 218 Ziqiang Street, 130041, Changchun, Jilin, ChinaDepartment of Orthopedics, The Second Hospital of Jilin University, No. 218 Ziqiang Street, 130041, Changchun, Jilin, ChinaDepartment of Orthopedics, The Second Hospital of Jilin University, No. 218 Ziqiang Street, 130041, Changchun, Jilin, ChinaCorresponding author.; Department of Orthopedics, The Second Hospital of Jilin University, No. 218 Ziqiang Street, 130041, Changchun, Jilin, ChinaDepartment of Orthopedics, The Second Hospital of Jilin University, No. 218 Ziqiang Street, 130041, Changchun, Jilin, ChinaCorresponding author.; Department of Orthopedics, The Second Hospital of Jilin University, No. 218 Ziqiang Street, 130041, Changchun, Jilin, ChinaIn anterior cervical discectomy and fusion (ACDF), an interbody fusion device is an essential implant. An unsuitable interbody fusion device can cause postoperative complications, including subsidence and nonunion. We designed a customized intervertebral fusion device to reduce postoperative complications and validated it by finite element analysis. Herein, we built a non-homogeneous model of the C3-7 cervical spine. Three implant models (customized cage, commercial cage, and bone graft cage) were constructed and placed in the C45 cervical segment after ACDF surgery. The simulated range of motion (ROM), stress at the cage-bone interface, and stress on the cage and implants were compared under different conditions. The commercial cage showed maximum stress peaks at 40.3 MPa and 43.2 MPa in the inferior endplate of C4 and superior endplate of C5 under rotational conditions, higher compared to 29.7 MPa and 26.4 MPa, respectively, in the customized cage. The ROM was not significantly different between the three cages placed after ACDF. The stresses on the commercial cage were higher compared to the other two cages under all conditions. The bone graft in the customized cage was subject to higher stress than the commercial cage under all conditions, particularly lateral bending, wherein the maximum stress was 5.5 MPa. These results showed that a customized cage that better conformed to the vertebral anatomy was promising for reducing the risk of stress shielding and the occurrence of subsidence.http://www.sciencedirect.com/science/article/pii/S2405844023001305BiomechanicalCervicalCageACDFFinite element analysis |
| spellingShingle | Bin Sun Qing Han FengXu Sui AoBo Zhang Yang Liu Peng Xia JinCheng Wang XiaoYu Yang Biomechanical analysis of customized cage conforming to the endplate morphology in anterior cervical discectomy fusion: A finite element analysis Heliyon Biomechanical Cervical Cage ACDF Finite element analysis |
| title | Biomechanical analysis of customized cage conforming to the endplate morphology in anterior cervical discectomy fusion: A finite element analysis |
| title_full | Biomechanical analysis of customized cage conforming to the endplate morphology in anterior cervical discectomy fusion: A finite element analysis |
| title_fullStr | Biomechanical analysis of customized cage conforming to the endplate morphology in anterior cervical discectomy fusion: A finite element analysis |
| title_full_unstemmed | Biomechanical analysis of customized cage conforming to the endplate morphology in anterior cervical discectomy fusion: A finite element analysis |
| title_short | Biomechanical analysis of customized cage conforming to the endplate morphology in anterior cervical discectomy fusion: A finite element analysis |
| title_sort | biomechanical analysis of customized cage conforming to the endplate morphology in anterior cervical discectomy fusion a finite element analysis |
| topic | Biomechanical Cervical Cage ACDF Finite element analysis |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023001305 |
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