Contrast media extravasation injury: a prospective observational cohort study
Abstract Objective To identify the risk factors for moderate and severe contrast media extravasation and provide effective guidance to reduce the degree of extravasation injuries. Methods We observed 224 adult patients who underwent contrast media extravasation at Xiangya Hospital of Central South U...
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40001-023-01444-5 |
| _version_ | 1797577284669931520 |
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| author | Wanli Liu Pinghu Wang Hui Zhu Hui Tang Hongmei Guan Xiaoying Wang Chengxiang Wang Yao Qiu Lianxiang He |
| author_facet | Wanli Liu Pinghu Wang Hui Zhu Hui Tang Hongmei Guan Xiaoying Wang Chengxiang Wang Yao Qiu Lianxiang He |
| author_sort | Wanli Liu |
| collection | DOAJ |
| description | Abstract Objective To identify the risk factors for moderate and severe contrast media extravasation and provide effective guidance to reduce the degree of extravasation injuries. Methods We observed 224 adult patients who underwent contrast media extravasation at Xiangya Hospital of Central South University, Hunan Provincial Maternal and Child Healthcare Hospital, and Xiangya Changde Hospital, Hunan Province between January 1, 2018 and December 31, 2022. Risk factors for moderate extravasation injuries were evaluated using univariate and multivariate logistic regression. Results Among 224 patients, 0 (0%) had severe, 18 (8.0%) had moderate, and 206 (92.0%) had mild contrast media extravasation injury. Multivariate logistic regression analysis revealed malignant tumors (odds ratio [OR] = 6.992, 95% confidence interval [CI]: 1.674–29.208), Iohexol (OR = 9.343, 95% CI 1.280–68.214), large-volume (> 50 mL) extravasation (OR = 5.773, 95% CI 1.350‒24.695), and injection site (back of the hand) (OR = 13.491, 95% CI 3.056–59.560) as independent risk factors for moderate injury. Conclusion Risk factors for moderate contrast media extravasation injury are malignant tumors, iohexol, large-volume (> 50 mL) extravasation, and back-of-the-hand injection. Analysis of these risk factors can help reduce the degree of injury after extravasation. Clinical relevance statement High-risk patients with extravasation support should choose the appropriate contrast media type, avoiding back-of-the-hand injections. We recommend that patients with cancer be implanted with a high-pressure resistant central venous catheter and receive effective measures to timely detect and reduce extravasation. |
| first_indexed | 2024-03-10T22:06:04Z |
| format | Article |
| id | doaj.art-1d177316c79e4f8abc140a41a8161096 |
| institution | Directory Open Access Journal |
| issn | 2047-783X |
| language | English |
| last_indexed | 2024-03-10T22:06:04Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj.art-1d177316c79e4f8abc140a41a81610962023-11-19T12:47:18ZengBMCEuropean Journal of Medical Research2047-783X2023-10-012811810.1186/s40001-023-01444-5Contrast media extravasation injury: a prospective observational cohort studyWanli Liu0Pinghu Wang1Hui Zhu2Hui Tang3Hongmei Guan4Xiaoying Wang5Chengxiang Wang6Yao Qiu7Lianxiang He8Teaching and Research Section of Clinical Nursing, Xiangya Hospital, Central South UniversityBreast Surgery Department, Hunan Provincial Maternal and Child Healthcare HospitalXiangya Changde HospitalTeaching and Research Section of Clinical Nursing, Xiangya Hospital, Central South UniversityTeaching and Research Section of Clinical Nursing, Xiangya Hospital, Central South UniversityXiangya Changde HospitalXiangya Changde HospitalXiangya Changde HospitalTeaching and Research Section of Clinical Nursing, Xiangya Hospital, Central South UniversityAbstract Objective To identify the risk factors for moderate and severe contrast media extravasation and provide effective guidance to reduce the degree of extravasation injuries. Methods We observed 224 adult patients who underwent contrast media extravasation at Xiangya Hospital of Central South University, Hunan Provincial Maternal and Child Healthcare Hospital, and Xiangya Changde Hospital, Hunan Province between January 1, 2018 and December 31, 2022. Risk factors for moderate extravasation injuries were evaluated using univariate and multivariate logistic regression. Results Among 224 patients, 0 (0%) had severe, 18 (8.0%) had moderate, and 206 (92.0%) had mild contrast media extravasation injury. Multivariate logistic regression analysis revealed malignant tumors (odds ratio [OR] = 6.992, 95% confidence interval [CI]: 1.674–29.208), Iohexol (OR = 9.343, 95% CI 1.280–68.214), large-volume (> 50 mL) extravasation (OR = 5.773, 95% CI 1.350‒24.695), and injection site (back of the hand) (OR = 13.491, 95% CI 3.056–59.560) as independent risk factors for moderate injury. Conclusion Risk factors for moderate contrast media extravasation injury are malignant tumors, iohexol, large-volume (> 50 mL) extravasation, and back-of-the-hand injection. Analysis of these risk factors can help reduce the degree of injury after extravasation. Clinical relevance statement High-risk patients with extravasation support should choose the appropriate contrast media type, avoiding back-of-the-hand injections. We recommend that patients with cancer be implanted with a high-pressure resistant central venous catheter and receive effective measures to timely detect and reduce extravasation.https://doi.org/10.1186/s40001-023-01444-5Contrast mediaExtravasationModerate extravasation injuryRisk factor |
| spellingShingle | Wanli Liu Pinghu Wang Hui Zhu Hui Tang Hongmei Guan Xiaoying Wang Chengxiang Wang Yao Qiu Lianxiang He Contrast media extravasation injury: a prospective observational cohort study European Journal of Medical Research Contrast media Extravasation Moderate extravasation injury Risk factor |
| title | Contrast media extravasation injury: a prospective observational cohort study |
| title_full | Contrast media extravasation injury: a prospective observational cohort study |
| title_fullStr | Contrast media extravasation injury: a prospective observational cohort study |
| title_full_unstemmed | Contrast media extravasation injury: a prospective observational cohort study |
| title_short | Contrast media extravasation injury: a prospective observational cohort study |
| title_sort | contrast media extravasation injury a prospective observational cohort study |
| topic | Contrast media Extravasation Moderate extravasation injury Risk factor |
| url | https://doi.org/10.1186/s40001-023-01444-5 |
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