Mesenchymal stem cell-derived extracellular vesicles prevent the development of osteoarthritis via the circHIPK3/miR-124-3p/MYH9 axis

Mesenchymal stem cell-derived extracellular vesicles prevent the development of osteoarthritis via the circHIPK3/miR-124-3p/MYH9 axis

Abstract Background Extracellular vesicles (EVs) secreted by mesenchymal stem cells (MSCs) may play a vital role in a variety of biological processes, including cartilage regeneration. However, few studies reported their potential in the development of osteoarthritis (OA) previously. In this study,...

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Bibliographic Details
Main Authors: Shenglong Li, Jie Liu, Siyu Liu, Weijie Jiao, Xiaohong Wang
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Nanobiotechnology
Subjects:
Mesenchymal stem cells (MSCs)
Extracellular vesicles
Osteoarthritis
Circular RNA HIPK3 (circHIPK3)
MiR-124-3p
MYH9
Online Access:https://doi.org/10.1186/s12951-021-00940-2

Internet

https://doi.org/10.1186/s12951-021-00940-2

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