MULTIFOCAL EPILEPSY – VIEW OF MODERN NEUROPHYSIOLOGIST

Data of own examinations and literature analysis regarding multifocal epilepsy are presented in the article. The analysis of etiology, clinical implications and prognostic factors of multifocal epilepsy of children and adults was done. It was discovered that the reasons of multifocal epilepsy in chi...

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Main Authors: V. O. Generalov, G. N. Avakyan, T. R. Sadykov, Yu. V. Kazakova
Format: Article
Language:Russian
Published: IRBIS LLC 2016-09-01
Series:Эпилепсия и пароксизмальные состояния
Subjects:
Online Access:https://www.epilepsia.su/jour/article/view/259
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author V. O. Generalov
G. N. Avakyan
T. R. Sadykov
Yu. V. Kazakova
author_facet V. O. Generalov
G. N. Avakyan
T. R. Sadykov
Yu. V. Kazakova
author_sort V. O. Generalov
collection DOAJ
description Data of own examinations and literature analysis regarding multifocal epilepsy are presented in the article. The analysis of etiology, clinical implications and prognostic factors of multifocal epilepsy of children and adults was done. It was discovered that the reasons of multifocal epilepsy in children are epileptic encephalopathies, genetic canalopathies and consequences of perinatal brain lesions. Formation of multifocal epilepsy in adults is associated with traumatic, ischemic and toxic factors, etc. Localization of epileptic sources is directly associated with zone of lesion: the source is located perifocally to zone of lesion in the structure or mediobasal temporal zones, that are more sensitive to diffusive effect of lesion (toxic and ischemic). More often localization of sources of epileptic activities in children is not associated with lesion character and zone. Multifocal epilepsy in children has very unfavorable prognosis, especially if caused by current pathological process (epileptic encephalopathy, neuroinfection). And on the contrary, multifocal epilepsy in adults is more successfully treated.
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spelling doaj.art-1d1928472c974e42a2ff20cdec78f47d2025-03-02T10:17:03ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882016-09-01421320258MULTIFOCAL EPILEPSY – VIEW OF MODERN NEUROPHYSIOLOGISTV. O. Generalov0G. N. Avakyan1T. R. Sadykov2Yu. V. Kazakova3Center of introduction of advanced medical technologies “Planeta Med” (Moscow)GBOU VPO Russian National Investigational Medical University” named after N.I. Pirogov, Ministry of Health and Social Development of the Russian Federation (Moscow)Center of introduction of advanced medical technologies “Planeta Med” (Moscow)Center of introduction of advanced medical technologies “Planeta Med” (Moscow)Data of own examinations and literature analysis regarding multifocal epilepsy are presented in the article. The analysis of etiology, clinical implications and prognostic factors of multifocal epilepsy of children and adults was done. It was discovered that the reasons of multifocal epilepsy in children are epileptic encephalopathies, genetic canalopathies and consequences of perinatal brain lesions. Formation of multifocal epilepsy in adults is associated with traumatic, ischemic and toxic factors, etc. Localization of epileptic sources is directly associated with zone of lesion: the source is located perifocally to zone of lesion in the structure or mediobasal temporal zones, that are more sensitive to diffusive effect of lesion (toxic and ischemic). More often localization of sources of epileptic activities in children is not associated with lesion character and zone. Multifocal epilepsy in children has very unfavorable prognosis, especially if caused by current pathological process (epileptic encephalopathy, neuroinfection). And on the contrary, multifocal epilepsy in adults is more successfully treated.https://www.epilepsia.su/jour/article/view/259multifocal epilepsyepileptic encephalopathynonlesional epilepsylesional epilepsyvideoencephalographic monitoring
spellingShingle V. O. Generalov
G. N. Avakyan
T. R. Sadykov
Yu. V. Kazakova
MULTIFOCAL EPILEPSY – VIEW OF MODERN NEUROPHYSIOLOGIST
Эпилепсия и пароксизмальные состояния
multifocal epilepsy
epileptic encephalopathy
nonlesional epilepsy
lesional epilepsy
videoencephalographic monitoring
title MULTIFOCAL EPILEPSY – VIEW OF MODERN NEUROPHYSIOLOGIST
title_full MULTIFOCAL EPILEPSY – VIEW OF MODERN NEUROPHYSIOLOGIST
title_fullStr MULTIFOCAL EPILEPSY – VIEW OF MODERN NEUROPHYSIOLOGIST
title_full_unstemmed MULTIFOCAL EPILEPSY – VIEW OF MODERN NEUROPHYSIOLOGIST
title_short MULTIFOCAL EPILEPSY – VIEW OF MODERN NEUROPHYSIOLOGIST
title_sort multifocal epilepsy view of modern neurophysiologist
topic multifocal epilepsy
epileptic encephalopathy
nonlesional epilepsy
lesional epilepsy
videoencephalographic monitoring
url https://www.epilepsia.su/jour/article/view/259
work_keys_str_mv AT vogeneralov multifocalepilepsyviewofmodernneurophysiologist
AT gnavakyan multifocalepilepsyviewofmodernneurophysiologist
AT trsadykov multifocalepilepsyviewofmodernneurophysiologist
AT yuvkazakova multifocalepilepsyviewofmodernneurophysiologist