Listeria-vectored cervical cancer vaccine candidate strains reduce MDSCs via the JAK-STAT signaling pathway

Listeria-vectored cervical cancer vaccine candidate strains reduce MDSCs via the JAK-STAT signaling pathway

Abstract Background Immunosuppressive status is prevalent in cancer patients and increases the complexity of tumor immunotherapy. It has been found that Listeria-vectored tumor vaccines had the potential ability of two-side regulatory effect on the immune response during immunotherapy. Results The r...

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Bibliographic Details
Main Authors: Yunwen Zhang, Yao Lei, Qian Ou, Mengdie Chen, Sicheng Tian, Jing Tang, Ruidan Li, Qian Liang, Zhaobin Chen, Chuan Wang
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Biology
Subjects:
Listeria-vectored tumor vaccines
Cervical cancer
Immunosuppression
MDSCs
JAK-STAT
Online Access:https://doi.org/10.1186/s12915-024-01876-3

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