Saquinavir-Piperine Eutectic Mixture: Preparation, Characterization, and Dissolution Profile

The dissolution rate of the anti-HIV drug saquinavir base (SQV), a poorly water-soluble and extremely low absolute bioavailability drug, was improved through a eutectic mixture formation approach. A screening based on a liquid-assisted grinding technique was performed using a 1:1 molar ratio of the...

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Bibliographic Details
Main Authors: Cinira Fandaruff, María Isabel Quirós-Fallas, José Roberto Vega-Baudrit, Mirtha Navarro-Hoyos, Diego German Lamas, Andrea Mariela Araya-Sibaja
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/10/2446