Myeloid lineage cells evince distinct steady-state level of certain gene groups in dependence on hereditary angioedema severity

Myeloid lineage cells evince distinct steady-state level of certain gene groups in dependence on hereditary angioedema severity

Hereditary angioedema (HAE) is a rare genetic disorder with variable expressivity even in carriers of the same underlying genetic defect, suggesting other genetic and epigenetic factors participate in modifying HAE severity. Recent knowledge indicates the role of immune cells in several aspects of H...

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Podrobná bibliografie
Hlavní autoři: Lucie Ballonová, Přemysl Souček, Peter Slanina, Kamila Réblová, Ondřej Zapletal, Marcela Vlková, Roman Hakl, Viktor Bíly, Hana Grombiříková, Eliška Svobodová, Petra Kulíšková, Julie Štíchová, Marta Sobotková, Radana Zachová, Jana Hanzlíková, Martina Vachová, Pavlína Králíčková, Irena Krčmová, Miloš Jeseňák, Tomáš Freiberger
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2023-07-01
Edice:Frontiers in Genetics
Témata:
FXII
hereditary angioedema
immune cell
interferon-gamma
gene expression
On-line přístup:https://www.frontiersin.org/articles/10.3389/fgene.2023.1123914/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1123914/full

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