Cyclophilin A Promotes Inflammation in Acute Kidney Injury but Not in Renal Fibrosis
Cyclophilin A (CypA) is a highly abundant protein in the cytoplasm of most mammalian cells. Beyond its homeostatic role in protein folding, CypA is a Damage-Associated Molecular Pattern which can promote inflammation during tissue injury. However, the role of CypA in kidney disease is largely unknow...
Main Authors: | Khai Gene Leong, Elyce Ozols, John Kanellis, David J. Nikolic-Paterson, Frank Y. Ma |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-05-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/10/3667 |
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