Research Progress of the Prevention and Treatment of Metabolic Diseases Based on Short Chain Fatty Acids
Short chain fatty acids (SCFAs) are a class of saturated fatty acids containing 1-6 carbon atoms, which are mainly produced by specific flora in the intestine through the fermentation of dietary fiber, and play an important role in maintaining the homeostasis of the intestinal environment. Recent st...
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| Format: | Article |
| Language: | zho |
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Chinese General Practice Publishing House Co., Ltd
2022-03-01
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| Series: | Zhongguo quanke yixue |
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| Online Access: | https://www.chinagp.net/fileup/1007-9572/PDF/yx2021123115.pdf |
| _version_ | 1827289864644591616 |
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| author | ZENG Lin, ZHANG Pengxiang, HUANG Qian, WANG Gaoxiang, LI Huilin |
| author_facet | ZENG Lin, ZHANG Pengxiang, HUANG Qian, WANG Gaoxiang, LI Huilin |
| author_sort | ZENG Lin, ZHANG Pengxiang, HUANG Qian, WANG Gaoxiang, LI Huilin |
| collection | DOAJ |
| description | Short chain fatty acids (SCFAs) are a class of saturated fatty acids containing 1-6 carbon atoms, which are mainly produced by specific flora in the intestine through the fermentation of dietary fiber, and play an important role in maintaining the homeostasis of the intestinal environment. Recent studies have shown that SCFAs can regulate glucose and lipid metabolism, regulate energy balance, maintain the intestinal barrier and reduce inflammatory responses, eventually participating in the occurrence and development of metabolic diseases such as type 2 diabetes mellitus, obesity, lipid metabolic disorders and nonalcoholic fat liver disease through the above multiple pathways. This article summarizes the mechanism of SCFAs regulating metabolism and the research progress in the prevention and treatment of metabolic diseases, in order to provide more reference materials for the prevention and treatment of metabolic diseases. |
| first_indexed | 2024-04-24T11:58:19Z |
| format | Article |
| id | doaj.art-1d1e04038aff48c7a8b0993a06a0eba3 |
| institution | Directory Open Access Journal |
| issn | 1007-9572 |
| language | zho |
| last_indexed | 2024-04-24T11:58:19Z |
| publishDate | 2022-03-01 |
| publisher | Chinese General Practice Publishing House Co., Ltd |
| record_format | Article |
| series | Zhongguo quanke yixue |
| spelling | doaj.art-1d1e04038aff48c7a8b0993a06a0eba32024-04-09T02:52:28ZzhoChinese General Practice Publishing House Co., LtdZhongguo quanke yixue1007-95722022-03-0125091141114710.12114/j.issn.1007-9572.2021.02.135Research Progress of the Prevention and Treatment of Metabolic Diseases Based on Short Chain Fatty AcidsZENG Lin, ZHANG Pengxiang, HUANG Qian, WANG Gaoxiang, LI Huilin0 1.The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine，Shenzhen 518033，China 2.Nanjing University of Chinese Medicine，Nanjing 210023，China 3.Shenzhen Traditional Chinese Medicine Hospital，Shenzhen 518033，China *Corresponding author：LI Huilin，Professor，Doctoral supervisor；E-mail：sztcmlhl@163.com Short chain fatty acids (SCFAs) are a class of saturated fatty acids containing 1-6 carbon atoms, which are mainly produced by specific flora in the intestine through the fermentation of dietary fiber, and play an important role in maintaining the homeostasis of the intestinal environment. Recent studies have shown that SCFAs can regulate glucose and lipid metabolism, regulate energy balance, maintain the intestinal barrier and reduce inflammatory responses, eventually participating in the occurrence and development of metabolic diseases such as type 2 diabetes mellitus, obesity, lipid metabolic disorders and nonalcoholic fat liver disease through the above multiple pathways. This article summarizes the mechanism of SCFAs regulating metabolism and the research progress in the prevention and treatment of metabolic diseases, in order to provide more reference materials for the prevention and treatment of metabolic diseases.https://www.chinagp.net/fileup/1007-9572/PDF/yx2021123115.pdf|fatty acids|short chain fatty acids|metabolic diseases|gastrointestinal microbiome|review |
| spellingShingle | ZENG Lin, ZHANG Pengxiang, HUANG Qian, WANG Gaoxiang, LI Huilin Research Progress of the Prevention and Treatment of Metabolic Diseases Based on Short Chain Fatty Acids Zhongguo quanke yixue |fatty acids|short chain fatty acids|metabolic diseases|gastrointestinal microbiome|review |
| title | Research Progress of the Prevention and
Treatment of Metabolic Diseases Based on Short Chain Fatty Acids |
| title_full | Research Progress of the Prevention and
Treatment of Metabolic Diseases Based on Short Chain Fatty Acids |
| title_fullStr | Research Progress of the Prevention and
Treatment of Metabolic Diseases Based on Short Chain Fatty Acids |
| title_full_unstemmed | Research Progress of the Prevention and
Treatment of Metabolic Diseases Based on Short Chain Fatty Acids |
| title_short | Research Progress of the Prevention and
Treatment of Metabolic Diseases Based on Short Chain Fatty Acids |
| title_sort | research progress of the prevention and treatment of metabolic diseases based on short chain fatty acids |
| topic | |fatty acids|short chain fatty acids|metabolic diseases|gastrointestinal microbiome|review |
| url | https://www.chinagp.net/fileup/1007-9572/PDF/yx2021123115.pdf |
| work_keys_str_mv | AT zenglinzhangpengxianghuangqianwanggaoxianglihuilin researchprogressofthepreventionandtreatmentofmetabolicdiseasesbasedonshortchainfattyacids |