Novel Iron-Chelating Prodrug Significantly Enhanced Fluorescence-Mediated Detection of Glioma Cells Experimentally In Vitro

Novel Iron-Chelating Prodrug Significantly Enhanced Fluorescence-Mediated Detection of Glioma Cells Experimentally In Vitro

(1) Background: The protoporphyrin IX (PpIX)-mediated fluorescence-guided resection and interoperative photodynamic therapy (PDT) of remaining cells may be effective adjuvants to the resection of glioma. Both processes may be enhanced by increasing intracellular PpIX concentrations, which can be ach...

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Bibliographic Details
Main Authors: Charlotte Reburn, George Gawthorpe, Alexis Perry, Mark Wood, Alison Curnow
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
fluorescence-guided resection (FGR)
photodynamic therapy (PDT)
iron chelation
protoporphyrin IX (PpIX)
glioma
AP2-18
Online Access:https://www.mdpi.com/1999-4923/15/12/2668

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